The liver is an immune organ that plays a vital role in the detection, capture, and clearance
of pathogens and foreign antigens that invade the human body. During acute and chronic …

Obtaining Plasmodium vivax sporozoites is essential for in vitro culture of liver stage
parasites, not only to understand fundamental aspects of parasite biology, but also for drug …

Dormancy enables relapsing malaria parasites, such as Plasmodium vivax and cynomolgi,
to survive unfavorable conditions. It is enabled by hypnozoites, parasites remaining …

Malaria is the leading human parasitosis and is transmitted through the bite of anopheline
mosquitoes infected with parasites of the genus Plasmodium spp. Among the seven species …

Radical cure of Plasmodium vivax malaria must include elimination of quiescent
'hypnozoite'forms in the liver; however, the only FDA-approved treatments are …

The protozoan parasite Plasmodium, causative agent of malaria, initially invades and
develops in hepatocytes where it resides in a parasitophorous vacuole (PV). A single …

Plasmodium vivax, one species of parasite causing human malaria, forms a dormant liver
stage, termed the hypnozoite, which activate weeks, months or years after the primary …

Background The zoonotic simian parasite Plasmodium cynomolgi develops into replicating
schizonts and dormant hypnozoites during the infection of hepatocytes and is used as a …

Trichothecenes (TCNs) are a large group of tricyclic sesquiterpenoid mycotoxins that have
intriguing structural features and remarkable biological activities. Herein, we focused on …

Protozoan parasites are known for their remarkable capacity to persist within the bodies of
vertebrate hosts, which frequently results in prolonged infections and the recurrence of …