Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease
L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …
related cardiovascular (CV) diseases in the coming decades that demands a deeper …
[HTML][HTML] Association between endodontic infection, its treatment and systemic health: a narrative review
SA Niazi, A Bakhsh - Medicina, 2022 - mdpi.com
The 'Focal Infection Era in Dentistry'in the late 19th and early 20th century resulted in
widespread implementation of tooth extraction and limited the progress of endodontics. The …
widespread implementation of tooth extraction and limited the progress of endodontics. The …
[HTML][HTML] Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19
R Mothes, A Pascual-Reguant, R Koehler… - Nature …, 2023 - nature.com
Prolonged lung pathology has been associated with COVID-19, yet the cellular and
molecular mechanisms behind this chronic inflammatory disease are poorly understood. In …
molecular mechanisms behind this chronic inflammatory disease are poorly understood. In …
Targeting of scavenger receptors stabilin-1 and stabilin-2 ameliorates atherosclerosis by a plasma proteome switch mediating monocyte/macrophage suppression
CP Manta, T Leibing, M Friedrich, H Nolte, M Adrian… - Circulation, 2022 - Am Heart Assoc
Background: Scavenger receptors Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are preferentially
expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating …
expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating …
[HTML][HTML] Molecular insight into pentraxin-3: Update advances in innate immunity, inflammation, tissue remodeling, diseases, and drug role
Abstract Pentraxin-3 (PTX3) is the prototype of the long pentraxin subfamily, an acute-phase
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …
[HTML][HTML] Interleukin-1β mediates arterial thrombus formation via NET-associated tissue factor
L Liberale, EW Holy, A Akhmedov, NR Bonetti… - Journal of clinical …, 2019 - mdpi.com
CANTOS reported reduced secondary atherothrombotic events in patients with residual
inflammatory risk treated with the inhibitory anti-IL-1β antibody, Canakinumab. Yet …
inflammatory risk treated with the inhibitory anti-IL-1β antibody, Canakinumab. Yet …
[HTML][HTML] Novel biomarkers of atherosclerotic vascular disease—Latest insights in the research field
The atherosclerotic vascular disease is a cardiovascular continuum in which the main role is
attributed to atherosclerosis, from its appearance to its associated complications. The …
attributed to atherosclerosis, from its appearance to its associated complications. The …
[HTML][HTML] Role of the renin–angiotensin system in the pathophysiology of coronary heart disease and heart failure: diagnostic biomarkers and therapy with drugs and …
JK Mehta, G Kaur, HS Buttar, HA Bagabir… - Frontiers in …, 2023 - frontiersin.org
The renin–angiotensin system (RAS) plays a pivotal role in blood pressure regulation. In
some cases, this steering mechanism is affected by various deleterious factors (mainly via …
some cases, this steering mechanism is affected by various deleterious factors (mainly via …
[HTML][HTML] Combining novel biomarkers for risk stratification of two-year cardiovascular mortality in patients with ST-elevation myocardial infarction
N Zagidullin, LJ Motloch, D Gareeva… - Journal of clinical …, 2020 - mdpi.com
ST-elevation myocardial infarction (STEMI) is one of the main reasons for morbidity and
mortality worldwide. In addition to the classic biomarker NT-proBNP, new biomarkers like …
mortality worldwide. In addition to the classic biomarker NT-proBNP, new biomarkers like …
[HTML][HTML] Cardiovascular biomarkers for prediction of in-hospital and 1-year post-discharge mortality in patients with COVID-19 pneumonia
LJ Motloch, P Jirak, D Gareeva, P Davtyan… - Frontiers in …, 2022 - frontiersin.org
Aims While COVID-19 affects the cardiovascular system, the potential clinical impact of
cardiovascular biomarkers on predicting outcomes in COVID-19 patients is still unknown …
cardiovascular biomarkers on predicting outcomes in COVID-19 patients is still unknown …