Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

Redox homeostasis is an essential requirement of the biological systems for performing
various normal cellular functions including cellular growth, differentiation, senescence …

Mitochondria are well known for their role in ATP production and biosynthesis of
macromolecules. Importantly, increasing experimental evidence points to the roles of …

Triple negative breast cancer (TNBC) is a deadly form of breast cancer due to the
development of resistance to chemotherapy affecting over 30% of patients. New …

Targeting altered tumour metabolism is an emerging therapeutic strategy for cancer
treatment. The metabolic reprogramming that accompanies the development of malignancy …

Cancer metabolic alterations have been emphasized to protect cancer cells from cell death.
The metabolic reprogramming toward a mesenchymal state makes cancer cells resistant to …

Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that lacks
targeted therapy options, and patients diagnosed with TNBC have poorer outcomes than …

Despite an increasing arsenal of anticancer therapies, many patients continue to have poor
outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of …

Signal transducer and activator of transcription (STAT) proteins are latent transcription
factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon …

Chemotherapy is one of the primary treatments for most human cancers. Despite great
progress in cancer therapeutics, chemotherapy continues to be important for improving the …