Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain
MW Ferenczy, LJ Marshall, CDS Nelson… - Clinical microbiology …, 2012 - Am Soc Microbiol
Progressive multifocal leukoencephalopathy (PML) is a debilitating and frequently fatal
central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which …
central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which …
Progressive multifocal leukoencephalopathy: current treatment options and future perspectives
D Pavlovic, AC Patera, F Nyberg… - Therapeutic …, 2015 - journals.sagepub.com
Progressive multifocal leukoencephalopathy (PML) is a rare but debilitating and frequently
fatal viral disease of the central nervous system, primarily affecting individuals with …
fatal viral disease of the central nervous system, primarily affecting individuals with …
HIV-associated opportunistic infections of the CNS
Survival in people infected with HIV has improved because of an increasingly powerful array
of antiretroviral treatments, but neurological symptoms due to comorbid conditions, including …
of antiretroviral treatments, but neurological symptoms due to comorbid conditions, including …
Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses
DF Florescu, MA Keck - Expert review of anti-infective therapy, 2014 - Taylor & Francis
CMX001 (hexadecyloxypropyl-cidofovir, Brincidofovir) is a broad spectrum, lipid conjugate
of cidofovir that is converted intracellularly into the active antiviral, cidofovir diphosphate …
of cidofovir that is converted intracellularly into the active antiviral, cidofovir diphosphate …
[HTML][HTML] In vitro comparison of currently available and investigational antiviral agents against pathogenic human double-stranded DNA viruses: A systematic literature …
Background Double-stranded (ds) DNA virus infections often occur concomitantly in
immunocompromised patients. We performed a systematic search of published in vitro …
immunocompromised patients. We performed a systematic search of published in vitro …
Advances in the development of antiviral strategies against parvovirus B19
E Manaresi, G Gallinella - Viruses, 2019 - mdpi.com
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …
[HTML][HTML] Development of CMX001 for the treatment of poxvirus infections
R Lanier, L Trost, T Tippin, B Lampert, A Robertson… - Viruses, 2010 - ncbi.nlm.nih.gov
Abstract CMX001 (phosphonic acid,[[(S)-2-(4-amino-2-oxo-1 (2H)-pyrimidinyl)-1-
(hydroxymethyl) ethoxy] methyl] mono [3-(hexadecyloxy) propyl] ester) is a lipid conjugate of …
(hydroxymethyl) ethoxy] methyl] mono [3-(hexadecyloxy) propyl] ester) is a lipid conjugate of …
Human polyomavirus reactivation: disease pathogenesis and treatment approaches
CF De Gascun, MJ Carr - Journal of Immunology Research, 2013 - Wiley Online Library
JC and BK polyomaviruses were discovered over 40 years ago and have become
increasingly prevalent causes of morbidity and mortality in a variety of distinct …
increasingly prevalent causes of morbidity and mortality in a variety of distinct …
Highlights in antiviral drug research: antivirals at the horizon
ED Clercq - Medicinal Research Reviews, 2013 - Wiley Online Library
This review highlights ten “hot topics” in current antiviral research:(i) new nucleoside
derivatives (ie, PSI‐352938) showing high potential as a direct antiviral against hepatitis C …
derivatives (ie, PSI‐352938) showing high potential as a direct antiviral against hepatitis C …
[HTML][HTML] Guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children: recommendations from the National Institutes …
GK Siberry, MJ Abzug, S Nachman… - The Pediatric …, 2013 - ncbi.nlm.nih.gov
This report updates the last version of the Guidelines for the Prevention and Treatment of
Opportunistic Infections (OIs) in HIV-Exposed and HIV-Infected Children, published in 2009 …
Opportunistic Infections (OIs) in HIV-Exposed and HIV-Infected Children, published in 2009 …