[HTML][HTML] Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters
G Diallinas - Frontiers in pharmacology, 2014 - frontiersin.org
Transporters are ubiquitous proteins mediating the translocation of solutes across cell
membranes, a biological process involved in nutrition, signaling, neurotransmission, cell …
membranes, a biological process involved in nutrition, signaling, neurotransmission, cell …
[HTML][HTML] Insights to the evolution of Nucleobase-Ascorbate Transporters (NAT/NCS2 family) from the Cys-scanning analysis of xanthine permease XanQ
S Frillingos - International journal of biochemistry and molecular …, 2012 - ncbi.nlm.nih.gov
The nucleobase-ascorbate transporter or nucleobase-cation symporter-2 (NAT/NCS2) family
is one of the five known families of transporters that use nucleobases as their principal …
is one of the five known families of transporters that use nucleobases as their principal …
The arrestin‐like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad‐range and specific signals
M Karachaliou, S Amillis, M Evangelinos… - Molecular …, 2013 - Wiley Online Library
We investigated the role of all arrestin‐like proteins of A spergillus nidulans in respect to
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …
[HTML][HTML] Functional identification of the hypoxanthine/guanine transporters YjcD and YgfQ and the adenine transporters PurP and YicO of Escherichia coli K-12
K Papakostas, M Botou, S Frillingos - Journal of Biological Chemistry, 2013 - ASBMB
The evolutionarily broad family nucleobase-cation symporter-2 (NCS2) encompasses
transporters that are conserved in binding site architecture but diverse in substrate …
transporters that are conserved in binding site architecture but diverse in substrate …
Transport assays in filamentous fungi: kinetic characterization of the UapC purine transporter of Aspergillus nidulans
E Krypotou, G Diallinas - Fungal Genetics and Biology, 2014 - Elsevier
Transport assays allow the direct kinetic analysis of a specific transporter by measuring
apparent K m and V max values, and permit the characterization of substrate specificity …
apparent K m and V max values, and permit the characterization of substrate specificity …
[HTML][HTML] Substrate selectivity of YgfU, a uric acid transporter from Escherichia coli
K Papakostas, S Frillingos - Journal of Biological Chemistry, 2012 - ASBMB
The ubiquitous nucleobase-ascorbate transporter (NAT/NCS2) family includes more than
2,000 members, but only 15 have been characterized experimentally. Escherichia coli has …
2,000 members, but only 15 have been characterized experimentally. Escherichia coli has …
Oligomerization of the UapA purine transporter is critical for ER-exit, plasma membrane localization and turnover
O Martzoukou, M Karachaliou, V Yalelis… - Journal of molecular …, 2015 - Elsevier
Central to the process of transmembrane cargo trafficking is the successful folding and exit
from the ER (endoplasmic r eticulum) through packaging in COPII vesicles. Here, we use the …
from the ER (endoplasmic r eticulum) through packaging in COPII vesicles. Here, we use the …
[HTML][HTML] Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 …
E Krypotou, V Kosti, S Amillis… - Journal of Biological …, 2012 - ASBMB
The recent elucidation of crystal structures of a bacterial member of the NCS1 family, the
Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to construct …
Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to construct …
[HTML][HTML] Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family
V Kosti, G Lambrinidis, V Myrianthopoulos… - PLoS …, 2012 - journals.plos.org
Using the crystal structure of the uracil transporter UraA of Escherichia coli, we constructed a
3D model of the Aspergillus nidulans uric acid-xanthine/H+ symporter UapA, which is a …
3D model of the Aspergillus nidulans uric acid-xanthine/H+ symporter UapA, which is a …
Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA
The AzgA purine/H+ symporter of A spergillus nidulans is the founding member of a
functionally and phylogenetically distinct transporter family present in fungi, bacteria and …
functionally and phylogenetically distinct transporter family present in fungi, bacteria and …