Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

J Lv, Y Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Fluoropolymers have unique physicochemical properties such as hydrophobicity and
lipophobicity, good chemical stability and bio-inertness, low surface energy and phase …

Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date

D Bobo, KJ Robinson, J Islam, KJ Thurecht… - Pharmaceutical …, 2016 - Springer
In this review we provide an up to date snapshot of nanomedicines either currently approved
by the US FDA, or in the FDA clinical trials process. We define nanomedicines as …

Harnessing endogenous stimuli for responsive materials in theranostics

AB Cook, P Decuzzi - ACS nano, 2021 - ACS Publications
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …

Star polymers

JM Ren, TG McKenzie, Q Fu, EHH Wong, J Xu… - Chemical …, 2016 - ACS Publications
Recent advances in controlled/living polymerization techniques and highly efficient coupling
chemistries have enabled the facile synthesis of complex polymer architectures with …

Machine-Learning-Guided Discovery of 19F MRI Agents Enabled by Automated Copolymer Synthesis

M Reis, F Gusev, NG Taylor, SH Chung… - Journal of the …, 2021 - ACS Publications
Modern polymer science suffers from the curse of multidimensionality. The large chemical
space imposed by including combinations of monomers into a statistical copolymer …

Antibiofouling polymer interfaces: poly (ethylene glycol) and other promising candidates

S Lowe, NM O'Brien-Simpson, LA Connal - Polymer Chemistry, 2015 - pubs.rsc.org
Nonspecific protein adsorption and/or microbial adsorption on biomedical materials
adversely affects the efficacy of a range of biomedical systems, from implants and …

19F Magnetic Resonance Imaging (MRI): From Design of Materials to Clinical Applications

I Tirotta, V Dichiarante, C Pigliacelli, G Cavallo… - Chemical …, 2015 - ACS Publications
To enable early monitoring of various diseases, to develop noninvasive diagnostic tools,
and to implement targeted therapies are some of the major challenges in current medicine …

[HTML][HTML] Living radical polymerization by the RAFT process–a third update

G Moad, E Rizzardo, SH Thang - Australian Journal of Chemistry, 2012 - CSIRO Publishing
This paper provides a third update to the review of reversible deactivation radical
polymerization (RDRP) achieved with thiocarbonylthio compounds (ZC (= S) SR) by a …

Surface-engineered dendrimers in gene delivery

J Yang, Q Zhang, H Chang, Y Cheng - Chemical reviews, 2015 - ACS Publications
1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …

Cell-penetrating hyperbranched polyprodrug amphiphiles for synergistic reductive milieu-triggered drug release and enhanced magnetic resonance signals

X Hu, G Liu, Y Li, X Wang, S Liu - Journal of the American …, 2015 - ACS Publications
The rational design of theranostic nanoparticles exhibiting synergistic turn-on of therapeutic
potency and enhanced diagnostic imaging in response to tumor milieu is critical for efficient …