Hollow hyper-cross-linked nanospheres with acid and base sites as efficient and water-stable catalysts for one-pot tandem reactions
A task-specific functionalized hyper-cross-linked polymer (HCP) with hollow spherical
structure was synthesized by an easily accessible Friedel–Crafts reaction-based approach …
structure was synthesized by an easily accessible Friedel–Crafts reaction-based approach …
Highly enantioselective [2+ 2]-cycloaddition reactions catalyzed by a chiral aluminum bromide complex
E Canales, EJ Corey - Journal of the American Chemical Society, 2007 - ACS Publications
Enantioselective [2+ 2]-cycloaddition pathways to chiral cyclobutanes are rare and not
generally utilized for synthesis. A new cycloaddition reaction of vinyl ethers with trifluoroethyl …
generally utilized for synthesis. A new cycloaddition reaction of vinyl ethers with trifluoroethyl …
Steroids: partial synthesis in medicinal chemistry
JR Hanson - Natural Product Reports, 2007 - pubs.rsc.org
Covering: January–December 2006 This article reviews the progress in the chemistry of the
steroids which was published between January and December 2006. The reactions and …
steroids which was published between January and December 2006. The reactions and …
Total synthesis of Alotaketal A
M Xuan, I Paterson, SM Dalby - Organic letters, 2012 - ACS Publications
The total synthesis of the cAMP signaling pathway activator (−)-alotaketal A is reported. A
convergent approach to the unusual alotane sesterterpenoid skeleton was employed …
convergent approach to the unusual alotane sesterterpenoid skeleton was employed …
N-heterocyclic carbene-catalyzed silyl enol ether formation
JJ Song, Z Tan, JT Reeves, DR Fandrick, NK Yee… - Organic …, 2008 - ACS Publications
N-Heterocyclic carbenes (NHCs) were found to catalyze the silyl transfer from trialkylsilyl
ketene acetals to ketones. In the presence of a catalytic amount of NHC 3 (IAd, 0.1 to 5 …
ketene acetals to ketones. In the presence of a catalytic amount of NHC 3 (IAd, 0.1 to 5 …
Ring C closure as key step in the synthesis of steroids
FCE Saraber, A de Groot - Tetrahedron, 2006 - Elsevier
Syntheses of steroids can be achieved by partial synthesis, modification of readily available
steroidal compounds or total synthesis. The latter is the most applied method and has been …
steroidal compounds or total synthesis. The latter is the most applied method and has been …
Formal synthesis of cortistatins
L Fang, Y Chen, J Huang, L Liu, J Quan, C Li, Z Yang - 2011 - ACS Publications
Formal Synthesis of Cortistatins | The Journal of Organic Chemistry ACS ACS Publications
C&EN CAS Find my institution Log In The Journal of Organic Chemistry ACS Publications …
C&EN CAS Find my institution Log In The Journal of Organic Chemistry ACS Publications …
Preparation of cis-γ-Hydroxycarvone Derivatives for Synthesis of Sesterterpenoid Natural Products: Total Synthesis of Phorbin A
JG Hubert, DP Furkert, MA Brimble - The Journal of Organic …, 2015 - ACS Publications
A robust synthetic approach to cis-γ-hydroxycarvone derivatives has been developed,
enabling efficient access to synthetic building blocks for the growing family of bioactive …
enabling efficient access to synthetic building blocks for the growing family of bioactive …
Design, synthesis and initial biological evaluation of a novel pladienolide analog scaffold
MK Gundluru, A Pourpak, X Cui, SW Morris… - Medchemcomm, 2011 - pubs.rsc.org
A novel and simplified synthetic scaffold based on pladienolide was designed using a
consensus pharmacophore hypothesis. An initial target was synthesized and evaluated to …
consensus pharmacophore hypothesis. An initial target was synthesized and evaluated to …
InCl3/Me3SiCl-Catalyzed Direct Michael Addition of Enol Acetates to α,β-Unsaturated Ketones
Y Onishi, Y Yoneda, Y Nishimoto, M Yasuda… - Organic letters, 2012 - ACS Publications
The direct Michael addition of enol acetates to α, β-unsaturated ketones was achieved using
a combination of Lewis acid catalysts, InCl3 and Me3SiCl, which furnished stable enol-form …
a combination of Lewis acid catalysts, InCl3 and Me3SiCl, which furnished stable enol-form …