Snail1 is the founding member of the Snail superfamily of zinc-finger transcription factors,
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …

The chromatin environment is essential for the correct specification and preservation of cell
identity through modulation and maintenance of transcription patterns. Many chromatin …

Epithelial-mesenchymal transition (EMT) and its critical roles during cancer progression
have long been recognized and extensively reviewed. Recent studies on the generation of …

The reprogramming factors that induce pluripotency have been identified primarily from
embryonic stem cell (ESC)-enriched, pluripotency-associated factors. Here, we report that …

Direct reprogramming of induced cardiomyocytes (iCMs) suffers from low efficiency and
requires extensive epigenetic repatterning, although the underlying mechanisms are largely …

Cell identity is a reflection of a cell type‐specific gene expression profile, and consequently,
cell type‐specific transcription factor networks are considered to be at the heart of a given …

Induced pluripotent stem cell (iPS) reprogramming allows to turn a differentiated somatic cell
into a pluripotent cell. This process is accompanied by many changes in fundamental cell …

Pluripotent stem cells, like embryonic stem cells (ESCs), have specialized epigenetic
landscapes, which are important for pluripotency maintenance. Transcription factor …

Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that
prescription and non-prescription drugs, herbal and dietary supplements can cause to the …

Because of their unique properties, multipotent mesenchymal stem cells (MSCs) represent
one of the most promising adult stem cells being used worldwide in a wide array of clinical …