The MEF2 transcription factors have roles in muscle, cardiac, skeletal, vascular, neural,
blood and immune system cell development through their effects on cell differentiation …

Follicular lymphoma (FL) is the most frequent indolent B cell lymphoma and is still
considered to be incurable. In recent years, whole-exome sequencing studies of large …

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-
cells. Prognosis is strongly associated with molecular subgroup, although the driver …

The majority of diffuse large B-cell lymphoma (DLBCL) tumors contain mutations in histone-
modifying enzymes (HMEs), indicating a potential therapeutic benefit of histone deacetylase …

The gene encoding the MEF2B transcription factor is mutated in germinal center (GC)-
derived B cell lymphomas, but its role in GC development and lymphomagenesis is …

Mantle cell lymphoma (MCL) is an uncommon B-cell non-Hodgkin lymphoma (NHL) that is
incurable with standard therapies. The genetic drivers of this cancer have not been firmly …

High-grade B-cell lymphoma accompanied with double/triple-hit MYC and BCL2 and/or
BCL6 rearrangements (HGBL-DH/TH) poses a cytogenetically-defined provisional entity …

Targeted next-generation sequencing panels are increasingly used to assess the value of
gene mutations for clinical diagnostic purposes. For assay development, amplicon-based …

Locus control region (LCR) functions define cellular identity and have critical roles in
diseases such as cancer, although the hierarchy of structural components and associated …

While MEF2 transcription factors are well known to cooperate in orchestrating cell fate and
adaptive responses during development and adult life, additional studies over the last …