Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances

V Soleimani, A Sahebkar… - Phytotherapy …, 2018 - Wiley Online Library
Curcumin is the major constituent of turmeric (Curcuma longa). Turmeric has been widely
used as a spice in foods and for therapeutic applications such as anti‐inflammatory …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Bioactivity, health benefits, and related molecular mechanisms of curcumin: Current progress, challenges, and perspectives

XY Xu, X Meng, S Li, RY Gan, Y Li, HB Li - Nutrients, 2018 - mdpi.com
Curcumin is a principal curcuminoid of turmeric (Curcuma longa), which is commonly used
as a spice in cooking and a yellow pigment in the food processing industry. Recent studies …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Inflammation, NF-κB, and chronic diseases: how are they linked?

AB Kunnumakkara, B Shabnam, S Girisa… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Most chronic diseases, caused by lifestyle factors, appear to be linked to inflammation.
Inflammation is activated mechanistically, and nuclear factor-κB (NF-κB) is a significant …

Curcumin supplementation and human disease: a scoping review of clinical trials

TM Panknin, CL Howe, M Hauer… - International Journal of …, 2023 - mdpi.com
Medicinal properties of turmeric (Curcuma longa L.), a plant used for centuries as an anti-
inflammatory, are attributed to its polyphenolic curcuminoids, where curcumin predominates …

Management of oral potentially malignant disorders

AR Kerr, G Lodi - Oral Diseases, 2021 - Wiley Online Library
Patients with oral potentially malignant disorders (OPMDs), including oral leukoplakia and
erythroplakia, proliferative verrucous leukoplakia, oral submucous fibrosis, and oral lichen …

Nivolumab for patients with high-risk oral leukoplakia: A nonrandomized controlled trial

GJ Hanna, A Villa, SP Nandi, R Shi, A ONeill… - JAMA …, 2024 - jamanetwork.com
Importance Proliferative verrucous leukoplakia (PVL) is an aggressive oral precancerous
disease characterized by a high risk of transformation to invasive oral squamous cell …

Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study

D Shep, C Khanwelkar, P Gade, S Karad - Trials, 2019 - Springer
Background The purpose of this study was to compare the efficacy and safety of curcumin
with those of diclofenac in the treatment of knee osteoarthritis (OA). Methods In this …