Sex steroids and autoimmune rheumatic diseases: state of the art

M Cutolo, RH Straub - Nature Reviews Rheumatology, 2020 - nature.com
In autoimmune rheumatic diseases, oestrogens can stimulate certain immune responses
(including effects on B cells and innate immunity), but can also have dose-related anti …

The role of female hormonal factors in the development of rheumatoid arthritis

D Alpízar-Rodríguez, N Pluchino, G Canny… - …, 2017 - academic.oup.com
RA is the most common chronic systemic autoimmune disease, with a higher prevalence in
women, suggesting female hormonal factors play a role in the development of the disease …

Environmental and gene-environment interactions and risk of rheumatoid arthritis

EW Karlson, K Deane - Rheumatic Disease Clinics of North America, 2012 - Elsevier
Multiple environmental factors including hormones, dietary factors, infections, and exposure
to tobacco smoke, as well as gene-environment interactions, have been associated with …

The importance of differences; On environment and its interactions with genes and immunity in the causation of rheumatoid arthritis

L Klareskog, J Rönnelid, S Saevarsdottir… - Journal of internal …, 2020 - Wiley Online Library
The current review uses rheumatoid arthritis (RA) as a prominent example for how studies
on the interplay between environmental and genetic factors in defined subsets of a disease …

Modifiable risk factors for RA: prevention, better than cure?

M Lahiri, C Morgan, DPM Symmons, IN Bruce - Rheumatology, 2012 - academic.oup.com
Objective. To perform a meta-synthesis of the evidence for modifiable lifestyle risk factors for
inflammatory polyarthritis (IP) and RA. Methods. We performed a MEDLINE literature search …

Early menopause is an independent predictor of rheumatoid arthritis

M Pikwer, U Bergström, JÅ Nilsson… - Annals of the …, 2012 - ard.bmj.com
Background As rheumatoid arthritis (RA) occurs more often in women than in men, it has
been suggested that reproductive hormones may play an important role in the pathogenesis …

What is the impact of sex hormones on the pathogenesis of rheumatoid arthritis?

C Raine, I Giles - Frontiers in Medicine, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease and has a
female predominance of around 3: 1. The relationship between sex hormones and RA has …

Environmental factors and hormones in the development of rheumatoid arthritis

D Alpízar-Rodríguez, A Finckh - Seminars in immunopathology, 2017 - Springer
The etiopathogenesis of rheumatoid arthritis (RA) is partially understood. Genetic,
environmental, and hormonal factors and their interactions are considered to play an …

Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study

C Orellana, S Saevarsdottir, L Klareskog… - Annals of the …, 2017 - ard.bmj.com
Objectives To study whether oral contraceptive (OC) use or breastfeeding (BF) influence the
risk of rheumatoid arthritis (RA), stratifying the cases by presence/absence of anticitrullinated …

Breastfeeding and risk of rheumatoid arthritis: a systematic review and metaanalysis

H Chen, J Wang, W Zhou, H Yin, M Wang - The Journal of rheumatology, 2015 - jrheum.org
Objective. Previous studies have examined the association between breastfeeding and
rheumatoid arthritis (RA), but their results were inconsistent. The aim of this study was to …