Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …

Recent emerging immunological treatments for primary brain tumors: focus on chemokine-targeting immunotherapies

A Ardizzone, R Basilotta, A Filippone, L Crupi, M Lanza… - Cells, 2023 - mdpi.com
Primary brain tumors are a leading cause of death worldwide and are characterized by
extraordinary heterogeneity and high invasiveness. Current drug and radiotherapy therapies …

CXCR2-blocking has context-sensitive effects on rat glioblastoma cell line outgrowth (S635) in an organotypic rat brain slice culture depending on microglia-depletion …

J Falter, A Lohmeier, P Eberl, EM Stoerr… - International Journal of …, 2023 - mdpi.com
In glioblastoma (GBM), the interplay of different immune cell subtypes, cytokines, and/or
drugs shows high context-dependencies. Interrelations between the routinely applied …

Crosstalk between cancer cells and macrophages promotes OSCC cell migration and invasion through a CXCL1/EGF positive feedback loop

W Huang, M Jiang, Y Lin, Y Qi, B Li - Discover Oncology, 2024 - Springer
Background CXC motif chemokine ligand 1 (CXCL1) and epithelial growth factor (EGF) are
highly secreted by oral squamous cell carcinoma (OSCC) cells and tumor-associated …

Bioinformatic analysis of the CXCR2 ligands in cancer processes

J Korbecki, M Bosiacki, D Chlubek… - International Journal of …, 2023 - mdpi.com
Human CXCR2 has seven ligands, ie, CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL7,
and CXCL8/IL-8—chemokines with nearly identical properties. However, no available study …