Magnetic iron oxide nanoparticle (IONP) synthesis to applications: present and future
Iron oxides are chemical compounds which have different polymorphic forms, including γ-
Fe2O3 (maghemite), Fe3O4 (magnetite), and FeO (wustite). Among them, the most studied …
Fe2O3 (maghemite), Fe3O4 (magnetite), and FeO (wustite). Among them, the most studied …
Iron oxide nanoparticles for biomedical applications: a perspective on synthesis, drugs, antimicrobial activity, and toxicity
Medical applications and biotechnological advances, including magnetic resonance
imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug …
imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug …
Antiepileptic drug-loaded and multifunctional iron oxide@ silica@ gelatin nanoparticles for acid-triggered drug delivery
The current study developed an innovative design for the production of smart multifunctional
core-double shell superparamagnetic nanoparticles (NPs) with a focus on the development …
core-double shell superparamagnetic nanoparticles (NPs) with a focus on the development …
Fighting Epilepsy with Nanomedicines—Is This the Right Weapon?
M Matias, AO Santos, S Silvestre, G Alves - Pharmaceutics, 2023 - mdpi.com
Epilepsy is a chronic and complex condition and is one of the most common neurological
diseases, affecting about 50 million people worldwide. Pharmacological therapy has been …
diseases, affecting about 50 million people worldwide. Pharmacological therapy has been …
Drug-resistant epilepsy: From multiple hypotheses to an integral explanation using preclinical resources
D Pérez-Pérez, CL Frías-Soria, L Rocha - Epilepsy & behavior, 2021 - Elsevier
Drug-resistant epilepsy affects approximately one-third of the patients with epilepsy. The
pharmacoresistant condition in epilepsy is mainly explained by six hypotheses. In addition …
pharmacoresistant condition in epilepsy is mainly explained by six hypotheses. In addition …
A window into the brain: Tools to assess pre-clinical efficacy of biomaterials-based therapies on central nervous system disorders
Therapeutic conveyance into the brain is a cardinal requirement for treatment of diverse
central nervous system (CNS) disorders and associated pathophysiology. Effectual …
central nervous system (CNS) disorders and associated pathophysiology. Effectual …
Nanotechnology-Based Formulations for Drug Targeting to the Central Nervous System
J Jampílek, K Králová - Nanoparticulate drug delivery systems, 2019 - taylorfrancis.com
Central nervous system (CNS) disorders have been incorporated into our daily lifestyle now
and in general, are faced by people of all age-groups and affect both men and women …
and in general, are faced by people of all age-groups and affect both men and women …
Noninvasive transcranial focal stimulation affects the convulsive seizure-induced P-glycoprotein expression and function in rats
D Pérez-Pérez, JL Castañeda-Cabral… - Epilepsy & Behavior, 2021 - Elsevier
Transcranial focal stimulation (TFS) is a noninvasive neuromodulation strategy that reduces
seizure activity in different experimental models. Nevertheless, there is no information about …
seizure activity in different experimental models. Nevertheless, there is no information about …
[HTML][HTML] Cannabidiol modifies the seizure expression and effects of antiseizure drugs in a rat model of recurrent severe seizures
CL Frías-Soria, D Pérez-Pérez, S Orozco-Suárez… - Seizure, 2021 - Elsevier
Purpose To evaluate the effects of cannabidiol alone or in combination with antiseizure
drugs in the expression of recurrent generalized seizures in a rat model. Methods Group A …
drugs in the expression of recurrent generalized seizures in a rat model. Methods Group A …
Standardization of research methods employed in assessing the interaction between metallic-based nanoparticles and the blood-brain barrier: Present and future …
Treating diseases of the central nervous system (CNS) is complicated by the presence of the
blood-brain barrier (BBB), a semipermeable boundary layer protecting the CNS from toxins …
blood-brain barrier (BBB), a semipermeable boundary layer protecting the CNS from toxins …