Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy
Gene editing-based therapeutic strategies grant the power to override cell machinery and
alter faulty genes contributing to disease development like cancer. Nowadays, the principal …
alter faulty genes contributing to disease development like cancer. Nowadays, the principal …
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells
M Farzanehpour, A Miri, AG Alvanegh… - Biochemical …, 2023 - Elsevier
The underlying cause of cancer is genetic disruption, so gene editing technologies,
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …
Distinct clinical and prognostic features of myelodysplastic syndrome in patients from the Middle East, North Africa, and beyond: A systemic review
A Al-Haidose, MA Yassin, MN Ahmed… - Journal of Clinical …, 2023 - mdpi.com
Myelodysplastic syndrome (MDS) describes a group of bone marrow malignancies with
variable morphologies and heterogeneous clinical features. The aim of this study was to …
variable morphologies and heterogeneous clinical features. The aim of this study was to …
Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment
M Valikhani, E Rahimian, SE Ahmadi… - … Hematology & Oncology, 2021 - Springer
Chromosomal translocations are the main etiological factor of hematologic malignancies.
These translocations are generally the consequence of aberrant DNA double-strand break …
These translocations are generally the consequence of aberrant DNA double-strand break …
[HTML][HTML] Higher prevalence of poor prognostic markers at a younger age in adult patients with myelodysplastic syndrome–evaluation of a large cohort in India
VM Srivastava, SC Nair, M Joy… - Molecular …, 2024 - molecularcytogenetics …
The karyotype is a major determinant of prognosis in myelodysplastic syndrome (MDS).
Details of the cytogenetic profile of MDS in South Asia are limited because cytogenetic …
Details of the cytogenetic profile of MDS in South Asia are limited because cytogenetic …
MDS/CMML from resource‐limited region: Characteristics and comparison to tertiary reference European center
A Sevoyan, A Mekinian, F Chermat… - European Journal of …, 2024 - Wiley Online Library
Abstract Introduction Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic
Leukemia (CMML) are clonal myeloid malignancies, characterized by bone marrow failure …
Leukemia (CMML) are clonal myeloid malignancies, characterized by bone marrow failure …
Myelodysplastic Syndromes at Middle East and North Africa (MENA) Centers: Case Study Upper Egypt
Background: Research on MDS is particularly sparse in the Middle East and North African
(MENA) regions, with Upper Egypt representing a distinct area in terms of geography …
(MENA) regions, with Upper Egypt representing a distinct area in terms of geography …