Mitochondrial homeostasis in VSMCs as a central hub in vascular remodeling

Y Xia, X Zhang, P An, J Luo, Y Luo - International journal of molecular …, 2023 - mdpi.com
Vascular remodeling is a common pathological hallmark of many cardiovascular diseases.
Vascular smooth muscle cells (VSMCs) are the predominant cell type lining the tunica media …

Mitochondrial transplantation as a novel therapeutic strategy for cardiovascular diseases

M Sun, W Jiang, N Mu, Z Zhang, L Yu, H Ma - Journal of Translational …, 2023 - Springer
Cardiovascular disease (CVD) is the leading cause of noncommunicable disease-related
death worldwide, and effective therapeutic strategies against CVD are urgently needed …

Prospects of mitochondrial transplantation in clinical medicine: Aspirations and challenges

S Hosseinian, PA Pour, A Kheradvar - Mitochondrion, 2022 - Elsevier
Mitochondria, known as the powerhouse of the cell, are at the center of healthy physiology
and provide cells with energy in the form of ATP. These unique organelles are also …

Mitochondrial transplantation as a possible therapeutic option for sarcopenia

I Turkel, B Ozerklig, M Yılmaz, O Ulger… - Journal of Molecular …, 2023 - Springer
With advancing age, the skeletal muscle phenotype is characterized by a progressive loss of
mass, strength, and quality. This phenomenon, known as sarcopenia, has a negative impact …

Targeting mitochondrial metabolic dysfunction in pulmonary hypertension: toward new therapeutic approaches?

M Riou, I Enache, F Sauer, AL Charles… - International journal of …, 2023 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare disease characterized by pulmonary
vascular remodeling leading to right heart failure and death. To date, despite the three …

[HTML][HTML] PEG-modified carbon-based nanoparticles as tumor-targeted drug delivery system reducing doxorubicin-induced cardiotoxicity

L Wang, X Xu, L Chu, C Meng, L Xu, Y Wang… - Biomedicine & …, 2023 - Elsevier
Herein, a doxorubicin-loaded carbon-based drug delivery system, denoted as PC-DOX,
composed of pH-responsive imine bond was developed for the tumor-targeted treatment. PC …

Mitochondrial transplantation in mitochondrial medicine: current challenges and future perspectives

M D'Amato, F Morra, I Di Meo, V Tiranti - International journal of molecular …, 2023 - mdpi.com
Mitochondrial diseases (MDs) are inherited genetic conditions characterized by pathogenic
mutations in nuclear DNA (nDNA) or mitochondrial DNA (mtDNA). Current therapies are still …

[HTML][HTML] Current advances of Mitochondrial dysfunction and cardiovascular disease and promising therapeutic strategies

D Xia, Y Liu, P Wu, D Wei - The American journal of pathology, 2023 - Elsevier
Mitochondria are “cellular power stations” and essential organelles for maintaining cellular
homeostasis. Dysfunctional mitochondria have emerged as a key factor in the occurrence …

Adipose derived mesenchymal stem cells-derived mitochondria transplantation ameliorated erectile dysfunction induced by cavernous nerve injury

J Zhai, Z Chen, P Chen, W Yang… - The World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Purpose Erectile dysfunction (ED) is a common postoperative complication of pelvic surgery
for which there is currently no effective treatment. This study investigated the therapeutic …

早期和晚期有氧运动对野百合碱诱导肺动脉高压大鼠右心衰竭的影响

孙园, 王庆博, 皮亦华, 陆春敏, 徐传仪, 张艳 - 中国组织工程研究, 2024 - cjter.com
早期和晚期有氧运动对野百合碱诱导肺动脉高压大鼠右心衰竭的影响 Page 1 Chinese Journal
of Tissue Engineering Research|Vol 28|No.2|January 2024|177 中国组织工程研究 Chinese …