The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …

For over 2000 years, ginseng (roots of Panax ginseng CA Meyer) has been used as a
traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng …

Chronic infections and cancers evade the host immune system through mechanisms that
induce T cell exhaustion. The heterogeneity within the exhausted CD8+ T cell pool has …

Although tumor immunotherapy has emerged as a promising therapeutic method for
oncology, it encounters several limitations, especially concerning low response rates and …

Epigenetic modification shapes differentiation trajectory and regulates the exhaustion state
of chimeric antigen receptor T (CAR-T) cells. Limited efficacy induced by terminal exhaustion …

For decades, scientists have been investigating how processes such as gene expression,
stem cell plasticity, and cell differentiation can be modulated. The discovery of epigenetics …

Immune checkpoint inhibitors (ICI) have achieved unprecedented clinical success in cancer
treatment. However, drug resistance to ICI therapy is a major hurdle that prevents cancer …

Monitoring T lymphocyte differentiation is essential for understanding T cell fate regulation
and advancing adoptive T cell immunotherapy. However, current biomarker analysis …

Purpose: Modified gemcitabine and S-1 (GS) is an active regimen for patients with advanced
biliary tract cancer (ABTC) in our previous study. Herein, we report the results of a single …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is persistently
threatening the lives of thousands of individuals globally. It triggers pulmonary oedema …