[HTML][HTML] Gut microbiota modulation of efficacy and toxicity of cancer chemotherapy and immunotherapy
D Chrysostomou, LA Roberts, JR Marchesi, JM Kinross - Gastroenterology, 2023 - Elsevier
Accumulating evidence supports not only the functional role of the gut microbiome in cancer
development and progression but also its role in defining the efficacy and toxicity of …
development and progression but also its role in defining the efficacy and toxicity of …
Antidepressive mechanisms of probiotics and their therapeutic potential
The accumulating knowledge of the host-microbiota interplay gives rise to the microbiota-gut-
brain (MGB) axis. The MGB axis depicts the interkingdom communication between the gut …
brain (MGB) axis. The MGB axis depicts the interkingdom communication between the gut …
Decorating bacteria with a therapeutic nanocoating for synergistically enhanced biotherapy
Disorders in the gut microbiota have been implicated in various diseases, such as
inflammatory bowel diseases, diabetes, and cancers. Oral microecologics are of great …
inflammatory bowel diseases, diabetes, and cancers. Oral microecologics are of great …
The ameliorative role of probiotics in 5-fluorouracil induced intestinal mucositis
AAXH Sim, JY Cheam, JWF Law… - … in Microbes and …, 2023 - research.monash.edu
Colorectal cancer (CRC) remains one of the top cancers in the world. Although early
detection improves the survival rate to around 90%, late detection would mean the need to …
detection improves the survival rate to around 90%, late detection would mean the need to …
The airway microbiome at birth
Alterations of pulmonary microbiome have been recognized in multiple respiratory
disorders. It is critically important to ascertain if an airway microbiome exists at birth and if so …
disorders. It is critically important to ascertain if an airway microbiome exists at birth and if so …
Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model
CW Chang, CY Liu, HC Lee, YH Huang, LH Li… - Frontiers in …, 2018 - frontiersin.org
Adjuvant 5-fluorouracil (5-FU)-based chemotherapy, including FOLFOX (5-FU, leucovorin,
and oxaliplatin), is recommended for colorectal cancer. However, intestinal mucositis …
and oxaliplatin), is recommended for colorectal cancer. However, intestinal mucositis …
Probiotics, prebiotics, synbiotics, and paraprobiotics as a therapeutic alternative for intestinal mucositis
VL Batista, TF Da Silva, LCL de Jesus… - Frontiers in …, 2020 - frontiersin.org
Intestinal mucositis, a cytotoxic side effect of the antineoplastic drug 5-fluorouracil (5-FU), is
characterized by ulceration, inflammation, diarrhea, and intense abdominal pain, making it …
characterized by ulceration, inflammation, diarrhea, and intense abdominal pain, making it …
Apoptosis, dysbiosis and expression of inflammatory cytokines are sequential events in the development of 5‐fluorouracil‐induced intestinal mucositis in mice
N Hamouda, T Sano, Y Oikawa, T Ozaki… - Basic & clinical …, 2017 - Wiley Online Library
Abstract The chemotherapeutic agent 5‐fluorouracil (5‐FU) causes intestinal mucositis with
severe diarrhoea, but the pathogenesis is not fully understood. In this study, we investigated …
severe diarrhoea, but the pathogenesis is not fully understood. In this study, we investigated …
Unlocking the potential of probiotics: a comprehensive review on research, production, and regulation of probiotics
TF da Silva, RA Glória, MF Americo, AS Freitas… - Probiotics and …, 2024 - Springer
This review provides a comprehensive overview of the current state of probiotic research,
covering a wide range of topics, including strain identification, functional characterization …
covering a wide range of topics, including strain identification, functional characterization …
Experimental chemotherapy-induced mucositis: a scoping review guiding the design of suitable preclinical models
J Huang, AYM Hwang, Y Jia, B Kim, M Iskandar… - International Journal of …, 2022 - mdpi.com
Mucositis is a common and most debilitating complication associated with the cytotoxicity of
chemotherapy. The condition affects the entire alimentary canal from the mouth to the anus …
chemotherapy. The condition affects the entire alimentary canal from the mouth to the anus …