Cancer vaccines: the next immunotherapy frontier
MJ Lin, J Svensson-Arvelund, GS Lubitz, A Marabelle… - Nature cancer, 2022 - nature.com
After several decades, therapeutic cancer vaccines now show signs of efficacy and potential
to help patients resistant to other standard-of-care immunotherapies, but they have yet to …
to help patients resistant to other standard-of-care immunotherapies, but they have yet to …
Head and neck cancer
Head and neck cancer is the seventh most common type of cancer worldwide and comprise
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …
Head and neck squamous cell carcinoma
DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …
Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and …
Squamous cell carcinoma of the head and neck (SCCHN) arises from epithelial cells and
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …
Treating head and neck cancer in the age of immunotherapy: a 2023 update
A Bhatia, B Burtness - Drugs, 2023 - Springer
Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …
present with locally advanced disease, requiring multimodality therapy. While this approach …
Human papillomavirus as a driver of head and neck cancers
ME Sabatini, S Chiocca - British journal of cancer, 2020 - nature.com
The human papillomavirus (HPV) family includes more than 170 different types of virus that
infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical …
infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical …
The changing epidemiology of oral cancer: definitions, trends, and risk factors
DI Conway, M Purkayastha, IG Chestnutt - British dental journal, 2018 - nature.com
Key Points Discusses issues affecting the definition of oral cancer and makes the case that
emerging differences in the aetiology of the disease at different sites requires oral cavity …
emerging differences in the aetiology of the disease at different sites requires oral cavity …
[HTML][HTML] Immune biomarkers of response to immune-checkpoint inhibitors in head and neck squamous cell carcinoma
M Oliva, A Spreafico, M Taberna, L Alemany… - Annals of oncology, 2019 - Elsevier
Anti-programmed cell death protein 1 (PD-1) agents have become the standard of care for
platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) …
platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) …
New insights into oral cancer—Risk factors and prevention: A review of literature
S Irani - International Journal of Preventive Medicine, 2020 - pmc.ncbi.nlm.nih.gov
The oral cancer constitutes 48% of head and neck cancer cases. Ninety percent of oral
cancer cases are histologically diagnosed as oral squamous cell carcinomas (OSCCs) …
cancer cases are histologically diagnosed as oral squamous cell carcinomas (OSCCs) …
High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …