Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …

Certain cellular components of the eye, such as neural retina, are unable to regenerate and
replicate after destructive inflammation. Ocular immune privilege provides the eye with …

There is an ongoing controversy as to whether major histocompatibility complex (MHC)
matching is a solution for allogeneic stem cell transplantation. In the present study, we …

The ocular tissue microenvironment is immune-privileged and uses multiple
immunosuppressive mechanisms to prevent the induction of inflammation. The retinal …

Tubercular uveitis (TB-uveitis) remains a conundrum in the uveitis field, which is mainly
related to the diverse clinical phenotypes of TB-uveitis. Moreover, it remains difficult to …

Background Retinitis pigmentosa (RP) is a hereditary retinal disease which leads to visual
impairment. The onset and progression of RP has physiological consequences that affects …

purpose. To determine whether retinal pigment epithelial (RPE) cells can inhibit in vitro T-
cell activation during inflammatory conditions. methods. Primary cultured RPE cells were …

The interaction of programmed death-1 (PD-1) expressed on T cells with its ligands B7H1
(PDL1) and B7DC (PDL2) is known to be a mechanism of T cell inhibition. In the present …

Although several observations show local T cell recognition of retinal Ag, there has been no
direct demonstration that the APC were retinal derived, rather than recruited. In this study …