As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …

Aim: Provide an overview of current available LTBI diagnostic test including updates, future
developments and perspectives. Results: There is currently no test for the direct …

Background We conducted a review to compare the sensitivity, specificity, reproducibility,
and predictive ability of QuantiFERON-TB Gold Plus (QFT-Plus) with that of QuantiFERON …

Tuberculosis infection (TBI) is defined as a state of infection in which individuals host live
Mycobacterium tuberculosis with or without clinical signs of active TB. It is now understood …

Key Clinical Points Latent Tuberculosis Infection Prevention of progression from latent
tuberculosis infection (LTBI) to tuberculosis disease is an important individual and public …

Purpose The diagnostic accuracy of the interferon-gamma release assay (IGRA) in
immunosuppressed patients remains unclear. Methods A systematic review and meta …

Objective 1) to compare the QIAreach TM QuantiFERON-TB (QIAreach QFT) vs.
QuantiFERON®-TB Gold Plus assay (QFT-Plus) to detect tuberculosis (TB) infection; 2) to …

Objective HIV-infection increases the risk to progress to active-tuberculosis (TB). Detection
of latent TB infection (LTBI) is needed to eventually propose preventive-therapy and reduce …

Rationale In 2016, a new interferon-gamma release assay (IGRA) was introduced,
QuantiFERON-TB Gold Plus (QFT-Plus), claimed to have improved sensitivity in active …

Objectives High accuracy diagnostic screening tests for tuberculosis (TB) are required to
improve the diagnosis of both active TB and latent Mycobacterium tuberculosis (MTB) …