[HTML][HTML] The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives

S Wang, Y Zheng, F Yang, L Zhu, XQ Zhu… - Signal transduction and …, 2021 - nature.com
Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …

[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …

Pancreatic adenocarcinoma, version 2.2021, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2021 - jnccn.org
Pancreatic cancer is the fourth leading cause of cancer-related death among men and
women in the United States. A major challenge in treatment remains patients' advanced …

European evidence-based guidelines on pancreatic cystic neoplasms

European Study Group on Cystic Tumours of the … - Gut, 2018 - gut.bmj.com
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are
lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of …

[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges

AD Singhi, EJ Koay, ST Chari, A Maitra - Gastroenterology, 2019 - Elsevier
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …

Burden of pancreatic cancer: from epidemiology to practice

N Khalaf, HB El-Serag, HR Abrams, AP Thrift - Clinical Gastroenterology …, 2021 - Elsevier
Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide with
432,242 related deaths in 2018. Unlike other cancers, the incidence of pancreatic cancer …

Microbiota in pancreatic health and disease: the next frontier in microbiome research

RM Thomas, C Jobin - Nature Reviews Gastroenterology & Hepatology, 2020 - nature.com
Diseases intrinsic to the pancreas such as pancreatitis, pancreatic cancer and type 1
diabetes mellitus impart substantial health and financial burdens on society but identification …

Screening for pancreatic cancer: US preventive services task force reaffirmation recommendation statement

DK Owens, KW Davidson, AH Krist, MJ Barry… - Jama, 2019 - jamanetwork.com
Importance Pancreatic cancer is an uncommon cancer with an age-adjusted annual
incidence of 12.9 cases per 100 000 person-years. However, the death rate is 11.0 deaths …

Long-term risk of malignancy in branch-duct intraductal papillary mucinous neoplasms

H Oyama, M Tada, K Takagi, K Tateishi, T Hamada… - Gastroenterology, 2020 - Elsevier
Background & Aims Long-term outcomes of patients with branch-duct intraductal papillary
mucinous neoplasms (IPMNs), particularly those after 5 years of surveillance, have not been …

Single-cell transcriptomics of pancreatic cancer precursors demonstrates epithelial and microenvironmental heterogeneity as an early event in neoplastic progression

V Bernard, A Semaan, J Huang, FA San Lucas… - Clinical Cancer …, 2019 - AACR
Purpose: Early detection of pancreatic ductal adenocarcinoma (PDAC) remains elusive.
Precursor lesions of PDAC, specifically intraductal papillary mucinous neoplasms (IPMNs) …