Postsurgical adhesions are a common complication of surgical procedures that can lead to
postoperative pain, bowel obstruction, infertility, as well as complications with future …

The foreign body response (FBR) remains a clinical challenge in the field of biomaterials
due to its ability to elicit a chronic and sustained immune response. Modulating the immune …

Polypropylene meshes used in pelvic organ prolapse (POP) repair are hampered by
complications. Most POP meshes are highly unstable after tensioning ex vivo, as evidenced …

The application of engineering tools and techniques to studying women's health, including
biomaterials-based approaches, is a research field experiencing robust growth. Biomaterials …

The current urogynecological clinical meshes trigger unfavorable foreign body response
which leads to graft failure in the long term. To overcome the present challenge, we applied …

Purpose Transvaginal meshes for the treatment of Pelvic Organ Prolapse (POP) have been
associated with severe adverse events and have been banned for clinical use in many …

Implants like meshes for the reinforcement of tissues implement the formation of a persistent
inflammation with an ambient fibrotic reaction. In the inflammatory infiltrate several distinct …

Background Polypropylene (PP) mesh is widely used to reinforce tissues. The foreign body
reaction (FBR) to the implant is dominated by innate immune cells, especially macrophages …

Polypropylene (PPL) mesh is widely used in pelvic floor reconstructive surgery for prolapse
and stress urinary incontinence. However, some women, particularly those treated using …

Tissue engineering approaches for treating pelvic organ prol... : Current Opinion in Urology
Tissue engineering approaches for treating pelvic organ prolapse using a novel source of …