The vertebrate spinal cord comprises multiple functionally distinct neuronal cell types
arranged in characteristic positions. During development, these different types of neurons …

Understanding human brain development is of fundamental interest but is also very
challenging. Single-cell RNA-sequencing studies in mammals have revealed that brain …

The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …

The spinal cord receives input from peripheral sensory neurons and controls motor output by
regulating muscle innervating motor neurons. These functions are carried out by neural …

Retinal ganglion cells (RGCs), cone photoreceptors (cones), horizontal cells and amacrine
cells are the first classes of neurons produced in the retina. However, an important question …

In vertebrates, the ontogeny of microglia, the resident macrophages of the central nervous
system, initiates early during development from primitive macrophages. Although murine …

The embryonic diencephalon forms integration centers and relay stations in the forebrain.
Anecdotal expression studies suggest that the diencephalon contains multiple …

The peripheral nervous system (PNS) represents a highly heterogeneous entity with a broad
range of functions, ranging from providing communication between the brain and the body to …

Loss-of-function mutations in a human AMPA receptor-associated protein, ferric chelate
reductase 1-like (FRRS1L), are associated with a devastating neurological condition …

The hypothalamus displays staggering cellular diversity, chiefly established during
embryogenesis by the interplay of several signalling pathways and a battery of transcription …