The structure and function of the barrier layers restricting the free diffusion of substances
between the central nervous system (brain and spinal cord) and the systemic circulation is of …

The correct development of blood vessels is crucial for all aspects of tissue growth and
physiology in vertebrates. The formation of an elaborate hierarchically branched network of …

The recent emergence of highly transmissible SARS-CoV-2 variants illustrates the urgent
need to better understand the molecular details of the virus binding to its host cell and to …

A set of electrostatically charged, fluorescent, and superparamagnetic nanoprobes was
developed for targeting cancer cells without using any molecular biomarkers. The surface …

The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells.
In response to extracellular matrix signalling, these cells undergo epithelialization and …

During mouse pre-implantation development, the formation of the blastocoel, a fluid-filled
lumen, breaks the radial symmetry of the blastocyst. The factors that control the formation …

Atomic force microscopy (AFM)-based methods have matured into a powerful nanoscopic
platform, enabling the characterization of a wide range of biological and synthetic …

Atomic force microscopy (AFM) techniques provide a versatile platform for imaging and
manipulating living cells to single-molecule resolution, thereby enabling us to address …

Vascularization is among the top challenges that impede the clinical application of
engineered tissues. This challenge has spurred tremendous research endeavor, defined as …

The formation of epithelial tissues containing lumens requires not only the apical-basolateral
polarization of cells, but also the coordinated orientation of this polarity such that the apical …