[PDF][PDF] 3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography

J Frohn, D Pinkert-Leetsch… - Journal of …, 2020 - journals.iucr.org
A multiscale three-dimensional (3D) virtual histology approach is presented, based on two
configurations of propagation phase-contrast X-ray tomography, which have been …

Organ-on-a-chip: Its use in cardiovascular research

S Lim, SW Kim, IK Kim, BW Song… - Clinical Hemorheology …, 2023 - content.iospress.com
Abstract Organ-on-a-chip (OOAC) has attracted great attention during the last decade as a
revolutionary alternative to conventional animal models. This cutting-edge technology has …

Multiscale photonic imaging of the native and implanted cochlea

D Keppeler, CA Kampshoff… - Proceedings of the …, 2021 - National Acad Sciences
The cochlea of our auditory system is an intricate structure deeply embedded in the temporal
bone. Compared with other sensory organs such as the eye, the cochlea has remained …

Pericytes control vascular stability and auditory spiral ganglion neuron survival

Y Zhang, L Neng, K Sharma, Z Hou, A Johnson, J Song… - Elife, 2023 - elifesciences.org
The inner ear has a rich population of pericytes, a multi-functional mural cell essential for
sensory hair cell heath and normal hearing. However, the mechanics of how pericytes …

Associations Between Diabetes Mellitus and Sensorineural Hearing Loss from Humans and Animal Studies

EDV Williams, ME Rubio - Hearing Research, 2024 - Elsevier
There is controversy regarding the association and etiopathogenesis of diabetes mellitus
(DM) and sensorineural hearing loss (SNHL). Some studies support that SNHL develops …

Parameterisation and prediction of intra-canal cochlear structures

J Thiselton, T Hanekom - Annals of Biomedical Engineering, 2024 - Springer
Accurate 3D models of the cochlea are useful tools for research in the relationship between
the electrode array and nerve fibres. The internal geometry of the cochlear canal plays an …

In silico Single-Cell Analysis of Steroid-Responsive Gene Targets in the Mammalian Cochlea

L Nelson, B Lovett, JD Johns, S Gu, D Choi… - Frontiers in …, 2022 - frontiersin.org
Background Treatment of many types of hearing instability in humans, including sudden
sensorineural hearing loss, Meniere's disease, and autoimmune inner ear disease, rely …

Closing the gap between the auditory nerve and Cochlear implant electrodes: which Neurotrophin cocktail performs best for axonal outgrowth and is electrical …

D Schmidbauer, S Fink, F Rousset… - International Journal of …, 2023 - mdpi.com
Neurotrophins promote neurite outgrowth of auditory neurons and may help closing the gap
to cochlear implant (CI) electrodes to enhance electrical hearing. The best concentrations …

Multiscale and multimodal imaging for three-dimensional vascular and histomorphological organ structure analysis of the pancreas

GA Salg, V Steinle, J Labode, W Wagner… - Scientific Reports, 2024 - nature.com
Exocrine and endocrine pancreas are interconnected anatomically and functionally, with
vasculature facilitating bidirectional communication. Our understanding of this network …

Understanding the impact of modiolus porosity on stimulation of spiral ganglion neurons by cochlear implants

KK Sriperumbudur, R Appali, AW Gummer… - Scientific Reports, 2024 - nature.com
Moderate-to-profound sensorineural hearing loss in humans is treatable by electrically
stimulating the auditory nerve (AN) with a cochlear implant (CI). In the cochlea, the modiolus …