Sustained suppression of VEGF for treatment of retinal/choroidal vascular diseases
PA Campochiaro, A Akhlaq - Progress in retinal and eye research, 2021 - Elsevier
Neovascular age-related macular degeneration (NVAMD) is the most prevalent choroidal
vascular disease, and diabetic retinopathy (DR) and retinal vein occlusion (RVO) are the …
vascular disease, and diabetic retinopathy (DR) and retinal vein occlusion (RVO) are the …
[HTML][HTML] Involvement of cytokines in the pathogenesis of diabetic macular edema
H Noma, K Yasuda, M Shimura - International journal of molecular …, 2021 - mdpi.com
Diabetic macular edema (DME) is a critical complication of diabetic retinopathy, a condition
that arises from the breakdown of the blood–retinal barrier and the consequent increase in …
that arises from the breakdown of the blood–retinal barrier and the consequent increase in …
Diabetic macular edema with neuroretinal detachment: OCT and OCT-angiography biomarkers of treatment response to anti-VEGF and steroids
S Vujosevic, C Toma, E Villani, A Muraca, E Torti… - Acta …, 2020 - Springer
Purpose To assess and compare early changes in neuroinflammatory and vascular
parameters in diabetic macular edema (DME) with subfoveal neuroretinal detachment …
parameters in diabetic macular edema (DME) with subfoveal neuroretinal detachment …
[HTML][HTML] Pharmacology of corticosteroids for diabetic macular edema
SM Whitcup, JA Cidlowski, KG Csaky… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: Corticosteroids remain the mainstay of treatment for inflammatory diseases almost
80 years after their first clinical use. Topical ophthalmic formulations of corticosteroids have …
80 years after their first clinical use. Topical ophthalmic formulations of corticosteroids have …
[HTML][HTML] Molecular investigation of candidate genes for pyroptosis-induced inflammation in diabetic retinopathy
N Wang, L Ding, D Liu, Q Zhang, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Background Diabetic retinopathy is a diabetic microvascular complication. Pyroptosis, as a
way of inflammatory death, plays an important role in the occurrence and development of …
way of inflammatory death, plays an important role in the occurrence and development of …
The prokineticins: neuromodulators and mediators of inflammation and myeloid cell-dependent angiogenesis
L Negri, N Ferrara - Physiological reviews, 2018 - journals.physiology.org
The mammalian prokineticins family comprises two conserved proteins, EG-VEGF/PROK1
and Bv8/PROK2, and their two highly related G protein-coupled receptors, PKR1 and PKR2 …
and Bv8/PROK2, and their two highly related G protein-coupled receptors, PKR1 and PKR2 …
Targeting Tie2 for treatment of diabetic retinopathy and diabetic macular edema
PA Campochiaro, KG Peters - Current diabetes reports, 2016 - Springer
Tie2 is a tyrosine kinase receptor located predominantly on vascular endothelial cells that
plays a central role in vascular stability. Angiopoietin-1 (Angpt1), produced by perivascular …
plays a central role in vascular stability. Angiopoietin-1 (Angpt1), produced by perivascular …
[HTML][HTML] Suprachoroidal CLS-TA plus intravitreal aflibercept for diabetic macular edema: a randomized, double-masked, parallel-design, controlled study
MR Barakat, CC Wykoff, V Gonzalez, A Hu… - Ophthalmology …, 2021 - Elsevier
Purpose This study evaluated the potential safety, efficacy, and durability advantages of
investigational triamcinolone acetonide suspension (CLS-TA; Clearside Biomedical …
investigational triamcinolone acetonide suspension (CLS-TA; Clearside Biomedical …
Intravitreal steroids in diabetic macular edema
R Lattanzio, MV Cicinelli, F Bandello - Management of Diabetic …, 2017 - karger.com
Over the past decade, great strides have been made in the management of diabetic macular
edema (DME). Therapeutic alternatives now include focal/grid laser photocoagulation, vitreo …
edema (DME). Therapeutic alternatives now include focal/grid laser photocoagulation, vitreo …
Aqueous cytokine expression and higher order OCT biomarkers: assessment of the anatomic-biologic bridge in the IMAGINE DME study
Purpose To identify biomarkers for predicting response to anti− vascular endothelial growth
factor (VEGF) therapy in diabetic macular edema (DME) and evaluate any links between …
factor (VEGF) therapy in diabetic macular edema (DME) and evaluate any links between …