Intestinal organoids: A thriving and powerful tool for investigating dietary nutrients-intestinal homeostasis axis

D Zhang, X Zhou, W Zhou, SW Cui, S Nie - Food Research International, 2023 - Elsevier
Dietary nutrients regulate intestinal homeostasis through a variety of complex mechanisms,
to affect the host health. Nowadays, various models have been used to investigate the …

Relationship between 4-hydroxynonenal (4-HNE) as systemic biomarker of lipid peroxidation and metabolomic profiling of patients with prostate cancer

MN Perkovic, M Jaganjac, L Milkovic, T Horvat, D Rojo… - Biomolecules, 2023 - mdpi.com
An oxidative degradation product of the polyunsaturated fatty acids, 4-hydroxynonenal (4-
HNE), is of particular interest in cancer research due to its concentration-dependent …

Dietary vitamin A affects growth performance, intestinal development, and functions in weaned piglets by affecting intestinal stem cells

Z Wang, J Li, Y Wang, L Wang, Y Yin… - Journal of animal …, 2020 - academic.oup.com
Vitamin A (VA) is an important nutrient for weaning piglets. It plays a significant role in the
normal formation, development, and maintenance of epithelial cells. Previous studies have …

Exploitation of In Vivo-Emulated In Vitro System in Advanced Food Science

Y Li, P Li, X Yu, X Zheng, Q Gu - Journal of Agricultural and Food …, 2023 - ACS Publications
Reasonable model construction contributes to the accuracy of experimental results. Multiple
in vivo models offer reliable choices for effective evaluation, whereas their applications are …

Serum retinol and risk of overall and site-specific cancer in the ATBC study

M Hada, AM Mondul, SJ Weinstein… - American journal of …, 2020 - academic.oup.com
Retinol, the most biologically active form of vitamin A, might influence cancer-related
biological pathways. However, results from observational studies of serum retinol and …

Retinol is involved in the intestinal regeneration strengthens the intestinal barrier during refeeding in broiler chickens

Y WANG, H ZHOU, C Jing, Y WU, Y GUO, W Bo… - Journal of Integrative …, 2023 - Elsevier
Fasting is typically used before feed metabolizable energy assessment in broilers. Previous
studies have shown that fasting cause atrophy of the intestinal villus. Whether fasting affects …

The migration and fusion events related to ROCK activity strongly influence the morphology of chicken embryo intestinal organoids

M Pierzchalska, M Panek, M Grabacka - Protoplasma, 2019 - Springer
The method of organoid culture has become a tool widely used in gastrointestinal research,
but so far, the migration of organoids derived from gut epithelium and formed in 3D Matrigel …

Defined serum-free culture of human infant small intestinal organoids with predetermined doses of Wnt3a and R-spondin1 from surgical specimens

Y Matsumoto, H Koga, M Takahashi, K Suda… - Pediatric Surgery …, 2021 - Springer
Purpose Refinement of organoid technology is important for studying physiology and
disease of the intestine. We aimed to optimize defined serum-free conditions for human …

T helper cells modulate intestinal stem cell renewal and differentiation

M Biton, AL Haber, S Beyaz, N Rogel, C Smillie… - bioRxiv, 2017 - biorxiv.org
In the small intestine, a cellular niche of diverse accessory cell types supports the rapid
generation of mature epithelial cell types through self-renewal, proliferation, and …

Modulation of intestinal epithelial cell differentiation, maintenance and/or function through t cell action

A Haber, M Biton, N ROGEL, RH HERBST… - 2018 - Google Patents
SLZIZIJTGAYEKK-CIJSCKBQSA-N molport-023-220-247 Chemical compound C ([C@@
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