This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Forces that are associated with blood flow are major determinants of vascular
morphogenesis and physiology. Blood flow is crucial for blood vessel development during …

Ginseng is a highly valued herb in the Far East and has gained popularity in the West during
the last decade. There is extensive literature on the beneficial effects of ginseng and its …

Mechanical forces influence different cell types in our bodies. Among the earliest forces
experienced in mammals is blood movement in the vascular system. Blood flow starts at the …

Poikilothermic organisms are exposed to frequent changes in environmental conditions and
their survival depends on their ability to acclimate to such changes. Changes in ambient …

Biophysical signals act as potent regulators of stem cell function, lineage commitment, and
epigenetic status. In recent years, synthetic biomaterials have been used to study a wide …

The vascular myogenic response refers to the acute reaction of a blood vessel to a change
in transmural pressure. This response is critically important for the development of resting …

As blood flows, the vascular wall is constantly subjected to physical forces, which regulate
important physiological blood vessel responses, as well as being implicated in the …

Endothelial cells (ECs) lining blood vessel walls respond to shear stress, a fluid mechanical
force generated by flowing blood, and the EC responses play an important role in the …