Mechanisms of nausea and vomiting: current knowledge and recent advances in intracellular emetic signaling systems

W Zhong, O Shahbaz, G Teskey, A Beever… - International journal of …, 2021 - mdpi.com
Nausea and vomiting are common gastrointestinal complaints that can be triggered by
diverse emetic stimuli through central and/or peripheral nervous systems. Both nausea and …

Capsicum annuum L. and its bioactive constituents: A critical review of a traditional culinary spice in terms of its modern pharmacological potentials with toxicological …

SK Mandal, SK Rath, R Logesh, SK Mishra… - Phytotherapy …, 2023 - Wiley Online Library
Capsicum annuum L., commonly known as chili pepper, is used as an important spice
globally and as a crude drug in many traditional medicine systems. The fruits of C. annuum …

Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol

SD Banister, JC Arnold, M Connor… - ACS chemical …, 2019 - ACS Publications
Cannabis (Cannabis sativa) is the most widely used illicit drug in the world, with an
estimated 192 million users globally. The main psychoactive component of cannabis is (−) …

Cannabinoid hyperemesis syndrome: pathophysiology and treatment in the emergency department

JR Richards - The Journal of emergency medicine, 2018 - Elsevier
Background Cannabinoid hyperemesis syndrome (CHS) is a challenging clinical disorder.
CHS patients frequently present to the emergency department and may require treatment for …

TRPV1: a common denominator mediating antinociceptive and antiemetic effects of cannabinoids

K Louis-Gray, S Tupal, LS Premkumar - International Journal of Molecular …, 2022 - mdpi.com
The most common medicinal claims for cannabis are relief from chronic pain, stimulation of
appetite, and as an antiemetic. However, the mechanisms by which cannabis reduces pain …

Pharmacological management of cannabinoid hyperemesis syndrome: an update of the clinical literature

G Burillo-Putze, JR Richards… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Cannabinoid hyperemesis syndrome (CHS) is an uncommon but unique
disorder defined by recurrent abdominal pain, intractable nausea, and emesis in patients …

Cannabinoid hyperemesis syndrome survey and genomic investigation

EB Russo, C Spooner, L May, R Leslie… - Cannabis and …, 2022 - liebertpub.com
Background: Cannabinoid hyperemesis syndrome (CHS) is a diagnosis of exclusion with
intractable nausea, cyclic vomiting, abdominal pain, and hot bathing behavior associated …

Cannabinoid hyperemesis syndrome: a review of potential mechanisms

MV DeVuono, LA Parker - Cannabis and Cannabinoid Research, 2020 - liebertpub.com
Introduction: Cannabinoids have long been known for their ability to treat nausea and
vomiting. Recent reports, however, have highlighted the paradoxical proemetic effects of …

A pilot trial of topical capsaicin cream for treatment of cannabinoid hyperemesis syndrome

DJ Dean, N Sabagha, K Rose, A Weiss… - Academic …, 2020 - Wiley Online Library
Objectives Patients with cannabinoid hyperemesis syndrome (CHS) present frequently to
the emergency department. Previous case studies suggest dramatic symptomatic …

Efficacy and safety of topical capsaicin for cannabinoid hyperemesis syndrome in the emergency department

S Wagner, J Hoppe, M Zuckerman, K Schwarz… - Clinical …, 2020 - Taylor & Francis
Introduction: Cannabinoid hyperemesis syndrome (CHS) is a disorder of cyclic and recurrent
nausea, vomiting, and abdominal pain associated with high-frequency and extended …