The adaptive immune response is a major determinant of the clinical outcome after SARS-
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …

Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …

Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some …

In rare instances, pediatric SARS-CoV-2 infection results in a novel immunodysregulation
syndrome termed multisystem inflammatory syndrome in children (MIS-C). We compared …

Vaccines developed against SARS-CoV-2 have proven to be highly effective in preventing
symptomatic infection. Similarly, prior infection with SARS-CoV-2 has been shown to provide …

T cells can contribute to clearance of respiratory viruses that cause acute-resolving
infections such as SARS-CoV-2, helping to provide long-lived protection against disease …

Pre-existing SARS-CoV-2-reactive T cells have been identified in SARS-CoV-2-unexposed
individuals, potentially modulating COVID-19 and vaccination outcomes. Here, we provide …