Articular cartilage defects are prevalent and are potentially involved in the initiation of
osteoarthritis, yet the lack of efficient therapeutic options to treat cartilage defects represents …

Nanogels have been widely explored for drug delivery, but their applications in the tissue
engineering field are still quite recent. Regenerative medicine also demands controlled …

Advanced biomaterial‐guided delivery of gene vectors is an emerging and highly attractive
therapeutic solution for targeted articular cartilage repair, allowing for a controlled and …

Untreated articular cartilage damage normally results in osteoarthritis and even disability
that affects millions of people. However, both the existing surgical treatment and tissue …

Cartilage loss due to age‐related degeneration and mechanical trauma is a significant and
challenging problem in the field of surgical medicine. Unfortunately, cartilage tissue can be …

Introduction: The article presents the results of the functional tests to improve the
assessment of MIA-induced osteoarthritis development and the effectiveness of NSAID …

Gene therapy directly targets mutations causing disease, allowing for a specific treatment at
a molecular level. Adeno-associated virus (AAV) has been of increasing interest as a gene …

Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …

Lineal (poloxamers or Pluronic®) or X-shaped (poloxamines or Tetronic®) amphiphilic tri-
block copolymers of poly (ethylene oxide) and poly (propylene oxide)(PEO-PPO-PEO) have …

Cyclodextrins (CDs) are one of the most versatile substances produced by nature, and it is in
the aqueous biological environment where the multifaceted potential of CDs can be …