The solubility behavior of drugs remains one of the most challenging aspects in formulation
development. Solid dispersions (SD) and inclusion complexes (IC) are two of the most …

Perilla oil is abundant in α-linolenic acid, which is metabolized to long-chain n-3 fatty acids.
This study aimed to determine thermal stability and bioavailability of perilla oil that was …

The biopharmaceutical classification system groups low-solubility drugs into two groups: II
and IV, with high and low permeability, respectively. Most of the new drugs developed for …

We synthesized cinnamic acid derivatives of ethyl cinnamate (EC) and analyzed the
resulting products using 1H‐NMR and FTIR spectroscopy. The formation of the confirmed …

Counterion competitive complexation is a background process currently ignored by using
ionic hosts. Consequently, guest binding constants are strongly affected by the design of the …

Solubility is a crucial limiting factor in pharmaceutical research and contaminated site
remediation. Cyclodextrin, with its structure of hydrophilic exterior and hydrophobic cavity …

Binding of solutes to macromolecules is often influenced by steric effects caused by the 3D
structures of both binding partners. In this study, the 1: 1 α-cyclodextrin (αCD) binding …

In this review paper, the inclusion complexation between cyclodextrin molecules (CDs) and
guests is carefully discussed. According to the importance concept of the non-covalent …

Electron transfer reactions are concerted reactions. The term ''concerted''indicates there is
no intermediate and the reaction takes place via a unique transition state. Since almost all …

This article describes the structure of the inclusion complex that a β-cyclodextrin derivative 1,
which includes a benzene ring tethered to a cyclodextrin moiety via a C, C-glucopyranoside …