[HTML][HTML] Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments

SA Antar, NA Ashour, M Sharaky, M Khattab… - Biomedicine & …, 2023 - Elsevier
Nowadays, diabetes mellitus has emerged as a significant global public health concern with
a remarkable increase in its prevalence. This review article focuses on the definition of …

Modulating glycolysis to improve cancer therapy

C Chelakkot, VS Chelakkot, Y Shin, K Song - International Journal of …, 2023 - mdpi.com
Cancer cells undergo metabolic reprogramming and switch to a 'glycolysis-
dominant'metabolic profile to promote their survival and meet their requirements for energy …

Glycolysis rate-limiting enzymes: novel potential regulators of rheumatoid arthritis pathogenesis

J Zuo, J Tang, M Lu, Z Zhou, Y Li, H Tian, E Liu… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a classic autoimmune disease characterized by uncontrolled
synovial proliferation, pannus formation, cartilage injury, and bone destruction. The specific …

Involvement of trained immunity during autoimmune responses

VP Mora, RA Loaiza, JA Soto, K Bohmwald… - Journal of …, 2023 - Elsevier
Recently, it has been described that innate immune cells such as monocytes, macrophages,
and natural killer cells can develop a non-specific immune response induced by different …

Mitochondrial control for healthy and autoimmune T cells

L Jia, L Zhang, M Liu, H Ji, Z Wen, C Wang - Cells, 2023 - mdpi.com
T cells are critical players in adaptive immunity, driving the tissue injury and organ damage
of patients with autoimmune diseases. Consequently, investigations on T cell activation …

Glycolysis in tumor microenvironment as a target to improve cancer immunotherapy

C Xiao, H Tian, Y Zheng, Z Yang, S Li, T Fan… - Frontiers in Cell and …, 2022 - frontiersin.org
Cancer cells and immune cells all undergo remarkably metabolic reprogramming during the
oncogenesis and tumor immunogenic killing processes. The increased dependency on …

Glycometabolism reprogramming: Implications for cardiovascular diseases

G Peng, J Yan, L Chen, L Li - Progress in Biophysics and Molecular Biology, 2023 - Elsevier
Glycometabolism is well known for its roles as the main source of energy, which mainly
includes three metabolic pathways: oxidative phosphorylation, glycolysis and pentose …

Azithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation

N Vallet, S Le Grand, L Bondeelle… - Blood, The Journal …, 2022 - ashpublications.org
Administration of azithromycin after allogeneic hematopoietic stem cell transplantation for
hematologic malignancies has been associated with relapse in a randomized phase 3 …

[HTML][HTML] Reprogramming of glucose metabolism: the hallmark of malignant transformation and target for advanced diagnostics and treatments

Q Tang, S Wu, B Zhao, Z Li, Q Zhou, Y Yu… - Biomedicine & …, 2024 - Elsevier
Reprogramming of cancer metabolism has become increasingly concerned over the last
decade, particularly the reprogramming of glucose metabolism, also known as the" Warburg …

The relationship between CD4+ T cell glycolysis and their functions

S Liu, S Liao, L Liang, J Deng, Y Zhou - Trends in Endocrinology & …, 2023 - cell.com
CD4+ T cells are effector T cells (Teffs) produced by the differentiation of initial T cells in
peripheral lymphoid tissue after being attacked by antigens, and have an indispensable role …