Regulation of DNA fragmentation: the role of caspases and phosphorylation

I Kitazumi, M Tsukahara - The FEBS journal, 2011 - Wiley Online Library
DNA fragmentation is a hallmark of apoptosis that is induced by apoptotic stimuli in various
cell types. Apoptotic signal pathways, which eventually cause DNA fragmentation, are …

Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials

HS Budi, B Farhood - Environmental research, 2023 - Elsevier
Oral cancers consist of squamous cell carcinoma (SCC) and other malignancies in the
mouth with varying degrees of invasion and differentiation. For many years, different …

Investigation on the origin of sperm DNA fragmentation: role of apoptosis, immaturity and oxidative stress

M Muratori, L Tamburrino, S Marchiani, M Cambi… - Molecular …, 2015 - Springer
Sperm DNA fragmentation (sDF) represents a threat to male fertility, human reproduction
and the health of the offspring. The causes of sDF are still unclear, even if apoptosis …

The PARP family: insights into functional aspects of poly (ADP‐ribose) polymerase‐1 in cell growth and survival

T Jubin, A Kadam, M Jariwala, S Bhatt… - Cell …, 2016 - Wiley Online Library
PARP family members can be found spread across all domains and continue to be essential
molecules from lower to higher eukaryotes. Poly (ADP‐ribose) polymerase 1 (PARP‐1) …

[HTML][HTML] Oxidative stress in female cancers

GM Calaf, U Urzua, L Termini, F Aguayo - Oncotarget, 2018 - ncbi.nlm.nih.gov
Breast, cervical and ovarian cancers are highly prevalent in women worldwide.
Environmental, hormonal and viral-related factors are especially relevant in the …

Anticancerous potential of polysaccharides sequentially extracted from Polygonatum cyrtonema Hua in Human cervical cancer Hela cells

L Li, K Thakur, YY Cao, BY Liao, JG Zhang… - International journal of …, 2020 - Elsevier
The anticancerous effects of PCHPs (HBSS, CHSS, DASS, and CASS) were investigated on
Human cervical cancer Hela cells proliferation inhibition, cytotoxicity, caspase-3 activity, cell …

Edible coating enriched with cinnamon oil reduces the oxidative stress and improves the quality of strawberry fruit stored at room temperature

T Piechowiak, B Skóra - Journal of the Science of Food and …, 2023 - Wiley Online Library
BACKGROUND The present study aimed to assess the impact of a starch/gelatine coating
containing cinnamon oil on selected quality attributes and redox status in strawberry fruit …

Ferulic acid reinstates mitochondrial dynamics through PGC1α expression modulation in 6‐hydroxydopamine lesioned rats

E Anis, MF Zafeer, F Firdaus, SN Islam… - Phytotherapy …, 2020 - Wiley Online Library
Disruption of the tightly regulated mitochondrial dynamics and energy homeostasis leads to
oxidative stress and apoptotic cell death, as observed in neurodegenerative disorders such …

The recent advances of PD-1 and PD-L1 checkpoint signaling inhibition for breast cancer immunotherapy

P Setordzi, X Chang, Z Liu, Y Wu, D Zuo - European journal of …, 2021 - Elsevier
Over the past decade, there has been sustained research activity on programmed death-
1/programmed death-ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors for breast cancer …

Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB

R He, X Shi, M Zhou, Y Zhao, S Pan, C Zhao… - Toxicology and applied …, 2018 - Elsevier
The lysosome is emerging as a central regulator of the autophagic process, which plays a
critical role in tumor growth and chemoresistance. Alantolactone, which is a natural …