The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Gene therapy represents a promising cancer treatment featuring high efficacy and limited
side effects, but it is stymied by a lack of safe and efficient gene-delivery vectors. Cationic …

Polymeric nanoparticles-based therapeutics show great promise in the treatment of a wide
range of diseases, due to the flexibility in which their structures can be modified, with …

Strategies for bone tissue regeneration have been continuously evolving for the last 25
years since the introduction of the “tissue engineering” concept. The convergence of the life …

The safe use of inorganic nanoparticles (NPs) in biomedical applications remains an
unresolved issue. The present review presents an overview of the cytotoxic effects of …

Liposomes are vesicular structures made of lipids that are formed in aqueous solutions.
Structurally, they resemble the lipid membrane of living cells. Therefore, they have been …

Nondestructive introduction of genes, proteins, and small molecules into mammalian cells
with high efficiency is a challenging, yet critical, process. Here we demonstrate a simple …

Oral delivery is an attractive route to deliver therapeutics via nanoparticles due to its ease of
administration and patient compliance. This review discusses laboratory techniques for …

Nanomaterials are promising candidates to improve the delivery efficiency and control of
active agents such as DNA or drugs directly into cells. Here we demonstrate cell-culture …