Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …

Tityus serrulatus (Ts) is the main scorpion species of medical importance in Brazil. Ts venom
is composed of several compounds such as mucus, inorganic salts, lipids, amines …

Scorpion venoms have long captivated scientific researchers, primarily due to the potency
and specificity of the mechanism of action of their derived components. Among other …

G protein-coupled receptors (GPCRs) represent important drug targets, as they regulate
pivotal physiological processes and they have proved to be readily druggable. Natural …

Scorpion venom is a mixture of peptides, including antimicrobial, bradykinin-potentiating
and anionic peptides and small to medium proteins, such as ion channel toxins …

Arachnida is the largest class among the arthropods, constituting over 60,000 described
species (spiders, mites, ticks, scorpions, palpigrades, pseudoscorpions, solpugids and …

In Brazil, the scorpion species responsible for most severe incidents belong to the Tityus
genus and, among this group, T. serrulatus, T. bahiensis, T. stigmurus and T. obscurus are …

BmKbpp is a novel cationic and α-helical peptide from the Chinese scorpion Mesobuthus
martensii Karsch, of which function or biological activity has not been characterized so far …

Background Scorpionism is a public health problem in Brazil, and Tityus serrulatus (Ts) is
primarily responsible for severe accidents. The main toxic components of Ts venom are low …