[HTML][HTML] The MAL protein, an integral component of specialized membranes, in normal cells and cancer

A Rubio-Ramos, L Labat-de-Hoz, I Correas, MA Alonso - Cells, 2021 - mdpi.com
The MAL gene encodes a 17-kDa protein containing four putative transmembrane segments
whose expression is restricted to human T cells, polarized epithelial cells and myelin …

[HTML][HTML] Shedding light on membrane rafts structure and dynamics in living cells

JA Nieto-Garai, M Lorizate, FX Contreras - Biochimica et Biophysica Acta …, 2022 - Elsevier
Cellular membranes are fundamental building blocks regulating an extensive repertoire of
biological functions. These structures contain lipids and membrane proteins that are known …

Super‐Resolution Microscopy Using a Bioorthogonal‐Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in …

M Lorizate, O Terrones, JA Nieto‐Garai… - Small …, 2021 - Wiley Online Library
Despite more than 20 years of work since the lipid raft concept was proposed, the existence
of these nanostructures remains highly controversial due to the lack of noninvasive methods …

[HTML][HTML] A model for primary cilium biogenesis by polarized epithelial cells: role of the midbody remnant and associated specialized membranes

L Labat-de-Hoz, A Rubio-Ramos… - Frontiers in cell and …, 2021 - frontiersin.org
Primary cilia are solitary, microtubule-based protrusions surrounded by a ciliary membrane
equipped with selected receptors that orchestrate important signaling pathways that control …

[HTML][HTML] Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes

P Carravilla, A Dasgupta, G Zhurgenbayeva… - Biophysical Reports, 2021 - cell.com
Understanding the plasma membrane nanoscale organization and dynamics in living cells
requires microscopy techniques with high spatial and temporal resolution that permit for long …

[HTML][HTML] Cytokinetic abscission regulation in neural stem cells and tissue development

KC McNeely, ND Dwyer - Current stem cell reports, 2021 - Springer
Abstract Purpose of Review How stem cells balance proliferation with differentiation, giving
rise to specific daughter cells during development to build an embryo or tissue, remains an …

[HTML][HTML] Sphingomyelin depletion inhibits CXCR4 dynamics and CXCL12-mediated directed cell migration in human T cells

SR Gardeta, EM García-Cuesta, G D'Agostino… - Frontiers in …, 2022 - frontiersin.org
Sphingolipids, ceramides and cholesterol are integral components of cellular membranes,
and they also play important roles in signal transduction by regulating the dynamics of …

[HTML][HTML] 中间体残体与初级纤毛的关系及其在肿瘤生长中的作用

李正阳, 赵慧明, 李苏冰, 焦作义 - Journal of Zhejiang University …, 2024 - ncbi.nlm.nih.gov
最新研究表明, 初级纤毛细胞外发生途径与一种特殊细胞器—中间体残体相关。
中间体残体是细胞有丝分裂末期中间体脱落形成的点状细胞器, 中间体残体形成后在细胞表面 …

Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells

AI Oqua, K Chao, LE Eid, L Casteller, A Miguéns… - bioRxiv, 2024 - biorxiv.org
G protein-coupled receptors (GPCRs) are integral membrane proteins which closely interact
with their plasma membrane lipid microenvironment. Cholesterol is a plasma membrane …

Multi-dimensional and spatiotemporal correlative imaging at the plasma membrane of live cells to determine the continuum nano-to-micro scale lipid adaptation and …

M Bernabé-Rubio, M Bosch-Fortea, MA Alonso… - Methods, 2021 - Elsevier
The primary cilium is a specialized plasma membrane protrusion with important receptors for
signalling pathways. In polarized epithelial cells, the primary cilium assembles after the …