The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that belongs to
the family of basic helix-loop-helix transcription factors. Although the AhR was initially …

Over the past decade, PAS domains have been identified in dozens of signal transduction
molecules and various forms have been found in animals, plants, and prokaryotes. In this …

Regulatory B cells (Bregs) play a critical role in the control of autoimmunity and
inflammation. IL-10 production is the hallmark for the identification of Bregs. However, the …

There is growing evidence that fossil fuel combustion products act as adjuvants in the
immune system and may lead to enhancement of allergic inflammation. Through this …

NF-κB/Rel transcription factors regulate many genes involved in control of cellular
proliferation, neoplastic transformation, and apoptosis, including the c-myc oncogene …

Several studies have demonstrated the anti-inflammatory potential of mesenchymal stromal
cells (MSCs) isolated from bone marrow, adipose tissue, placenta, and other sources …

The polycyclic aromatic hydrocarbon, 7, 12-dimethylbenz [a] anthracene (DMBA), is an
immunosuppressor as well as a potent organ-specific carcinogen. To understand the organ …

Polycyclic aromatic hydrocarbons (PAHs) such as benzo (a) pyrene (BP) are ubiquitous
environmental carcinogenic contaminants exerting deleterious effects toward cells acting in …

Data mining published microarray experiments require that expression profiles are directly
comparable. We performed linear global normalization on the data of 1967 Affymetrix …

Inflammatory Breast Cancer (IBC) is a highly aggressive form of cancer characterized by
high rates of proliferation, lymphangiogenesis and metastasis, and an overall poor survival …