Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease

ST Lugg, A Scott, D Parekh, B Naidu, DR Thickett - Thorax, 2022 - thorax.bmj.com
Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic
lung disease and predisposes individuals to acute lung injury and pulmonary infection …

M1/M2 macrophages and their overlaps–myth or reality?

Z Strizova, I Benesova, R Bartolini… - Clinical …, 2023 - portlandpress.com
Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Living leukocyte‐based drug delivery systems

Y Chen, D Qin, J Zou, X Li, XD Guo, Y Tang… - Advanced …, 2023 - Wiley Online Library
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …

Macrophages: Their role, activation and polarization in pulmonary diseases

S Arora, K Dev, B Agarwal, P Das, MA Syed - Immunobiology, 2018 - Elsevier
Macrophages, circulating in the blood or concatenated into different organs and tissues
constitute the first barrier against any disease. They are foremost controllers of both innate …

Cross-talk between alveolar macrophages and lung epithelial cells is essential to maintain lung homeostasis

EY Bissonnette, JF Lauzon-Joset, JS Debley… - Frontiers in …, 2020 - frontiersin.org
The main function of the lung is to perform gas exchange while maintaining lung
homeostasis despite environmental pathogenic and non-pathogenic elements contained in …

Macrophage polarization and allergic asthma

A Saradna, DC Do, S Kumar, QL Fu, P Gao - Translational Research, 2018 - Elsevier
Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …

Macrophage polarization in pathology

A Sica, M Erreni, P Allavena, C Porta - Cellular and molecular life sciences, 2015 - Springer
Macrophages are cells of the innate immunity constituting the mononuclear phagocyte
system and endowed with remarkable different roles essential for defense mechanisms …

Macrophage biology in development, homeostasis and disease

TA Wynn, A Chawla, JW Pollard - Nature, 2013 - nature.com
Macrophages, the most plastic cells of the haematopoietic system, are found in all tissues
and show great functional diversity. They have roles in development, homeostasis, tissue …

IL33: roles in allergic inflammation and therapeutic perspectives

BCL Chan, CWK Lam, LS Tam, CK Wong - Frontiers in immunology, 2019 - frontiersin.org
Interleukin (IL)-33 belongs to IL-1 cytokine family which is constitutively produced from the
structural and lining cells including fibroblasts, endothelial cells, and epithelial cells of skin …

Macrophage plasticity and polarization in tissue repair and remodelling

A Mantovani, SK Biswas, MR Galdiero… - The Journal of …, 2013 - Wiley Online Library
Mononuclear phagocyte plasticity includes the expression of functions related to the
resolution of inflammation, tissue repair and remodelling, particularly when these cells are …