Hypericin-mediated photodynamic therapy for the treatment of cancer: a review

X Dong, Y Zeng, Z Zhang, J Fu, L You… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Hypericin is a polycyclic aromatic naphthodianthrone that occurs naturally. It is
also an active ingredient in some species of the genus Hypericum. Emerging evidence …

Hypericin: A natural anthraquinone as promising therapeutic agent

JJ Wu, J Zhang, CY Xia, K Ding, XX Li, XG Pan, JK Xu… - Phytomedicine, 2023 - Elsevier
Background: Hypericin is a prominent secondary metabolite mainly existing in genus
Hypericum. It has become a research focus for a quiet long time owing to its extensively …

Red LED light promotes biomass, flowering and secondary metabolites accumulation in hydroponically grown Hypericum perforatum L.(cv. Topas)

M Karimi, N Ahmadi, M Ebrahimi - Industrial Crops and Products, 2022 - Elsevier
To increase the crop yield and quality, the plant cultivation in equipped growing systems is
an alternative to open field production. Artificial light sources are a critical component in the …

Thermoresponsive liposomes for photo-triggered release of hypericin cyclodextrin inclusion complex for efficient antimicrobial photodynamic therapy

AA Dayyih, B Gutberlet, E Preis… - … Applied Materials & …, 2022 - ACS Publications
Antimicrobial strategies with high efficacy against bacterial infections are urgently needed.
The development of effective therapies to control bacterial infections is still a challenge …

Thermosensitive liposomes encapsulating hypericin: Characterization and photodynamic efficiency

AA Dayyih, M Alawak, AM Ayoub, MU Amin… - International journal of …, 2021 - Elsevier
The potent photodynamic properties of Hypericin (Hyp) elicit a range of light-dose-
dependent anti-tumor activities. However, its low water solubility hampers its broad …

Thermoresponsive hydrogel-loading aluminum chloride phthalocyanine as a drug release platform for topical administration in photodynamic therapy

EL de Oliveira, SBS Ferreira, LV de Castro-Hoshino… - Langmuir, 2021 - ACS Publications
Phthalocyanine aluminum chloride (Pc) is a clinically viable photosensitizer (PS) to treat skin
lesions worsened by microbial infections. However, this molecule presents a high self …

Alkyl Chain length in poly (2-oxazoline)-based amphiphilic gradient copolymers regulates the delivery of hydrophobic molecules: a case of the biodistribution and the …

V Huntosova, S Datta, L Lenkavska… - …, 2021 - ACS Publications
Self-assembled nanostructures of amphiphilic gradient copoly (2-oxazoline) s have recently
attracted attention as promising delivery systems for the effective delivery of hydrophobic …

Nanomedicine: A pragmatic approach for tackling melanoma skin cancer

VM Prajapat, S Mahajan, PG Paul, M Aalhate… - Journal of Drug Delivery …, 2023 - Elsevier
Melanoma is the most aggressive form of skin cancer and its annual incidence rates are
increasing globally. Though chemotherapy, radiotherapy, immunotherapy and targeted …

Progress in nanocarriers codelivery system to enhance the anticancer effect of photodynamic therapy

YL Yang, K Lin, L Yang - Pharmaceutics, 2021 - mdpi.com
Photodynamic therapy (PDT) is a promising anticancer noninvasive method and has great
potential for clinical applications. Unfortunately, PDT still has many limitations, such as …

Nanoparticle-based drug delivery systems for photodynamic therapy of metastatic melanoma: a review

NW Nkune, H Abrahamse - International Journal of Molecular Sciences, 2021 - mdpi.com
Metastatic melanoma (MM) is a skin malignancy arising from melanocytes, the incidence of
which has been rising in recent years. It poses therapeutic challenges due to its resistance …