Public health authorities have described, with growing alarm, an unprecedented increase in
morbidity and mortality associated with use of opioid pain relievers (OPRs). Efforts to …

Illicit use of opiates is the fastest growing substance use problem in the United States, and
the main reason for seeking addiction treatment services for illicit drug use throughout the …

Aims To examine patient and medication characteristics associated with retention and
continued illicit opioid use in methadone (MET) versus buprenorphine/naloxone (BUP) …

Objective Detoxification followed by abstinence has shown little success in reducing illicit
opioid use. Methadone maintenance treatment (MMT) helps individuals with an opioid use …

Drug use represents a significant burden to public health through disease, disability and
social problems, and policy makers are becoming increasingly interested in how to develop …

These Guidelinesreview the use of medicines such as methadone, buprenorphine,
naltrexone and clonidine in combination with psychosocial support in the treatment of …

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the
effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular …

Methadone is widely used for the treatment of opioid dependence. Although in most
countries the drug is administered as a racemic mixture of (R)-and (S)-methadone,(R) …

AIM: To summarize the major findings of the five Cochrane reviews on substitution
maintenance treatments for opioid dependence. METHODS: We conducted a narrative and …

Purpose The American Society of Addiction Medicine (ASAM) developed the National
Practice Guideline for the Treatment of Opioid Use Disorder (the Practice Guideline) to …