Calcium signalling in T cells
M Trebak, JP Kinet - Nature Reviews Immunology, 2019 - nature.com
Abstract Calcium (Ca2+) signalling is of paramount importance to immunity. Regulated
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …
[HTML][HTML] Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles
NR Tykocki, EM Boerman… - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
TRPC channels: Structure, function, regulation and recent advances in small molecular probes
Transient receptor potential canonical (TRPC) channels constitute a group of receptor-
operated calcium-permeable nonselective cation channels of the TRP superfamily. The …
operated calcium-permeable nonselective cation channels of the TRP superfamily. The …
Fundamentals of cellular calcium signaling: a primer
MD Bootman, G Bultynck - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Ionized calcium (Ca2+) is the most versatile cellular messenger. All cells use Ca2+ signals
to regulate their activities in response to extrinsic and intrinsic stimuli. Alterations in cellular …
to regulate their activities in response to extrinsic and intrinsic stimuli. Alterations in cellular …
Physiological functions of CRAC channels
SM Emrich, RE Yoast, M Trebak - Annual Review of Physiology, 2022 - annualreviews.org
Store-operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ signaling pathway that is
evolutionarily conserved across eukaryotes. SOCE is triggered physiologically when the …
evolutionarily conserved across eukaryotes. SOCE is triggered physiologically when the …
Ion channels and channelopathies in glomeruli
A Staruschenko, R Ma, O Palygin… - Physiological …, 2023 - journals.physiology.org
An essential step in renal function entails the formation of an ultrafiltrate that is delivered to
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …
the renal tubules for subsequent processing. This process, known as glomerular filtration, is …
[HTML][HTML] The connexin 43 C-terminus: A tail of many tales
Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …
communication between the cytosols of adjacent cells, create a unique cell signalling …
TRPC1, Orai1, and STIM1 in SOCE: Friends in tight spaces
IS Ambudkar, LB de Souza, HL Ong - Cell calcium, 2017 - Elsevier
Store-operated calcium entry (SOCE) is a ubiquitous Ca 2+ entry pathway that is activated in
response to depletion of ER-Ca 2+ stores and critically controls the regulation of …
response to depletion of ER-Ca 2+ stores and critically controls the regulation of …
[HTML][HTML] The native ORAI channel trio underlies the diversity of Ca2+ signaling events
RE Yoast, SM Emrich, X Zhang, P Xin… - Nature …, 2020 - nature.com
The essential role of ORAI1 channels in receptor-evoked Ca2+ signaling is well understood,
yet little is known about the physiological activation of the ORAI channel trio natively …
yet little is known about the physiological activation of the ORAI channel trio natively …
[HTML][HTML] DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
K Xu, S Sun, M Yan, J Cui, Y Yang, W Li… - Frontiers in …, 2022 - frontiersin.org
DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …