ACE2: the molecular doorway to SARS-CoV-2
MM Medina-Enríquez, S Lopez-León… - Cell & bioscience, 2020 - Springer
The angiotensin-converting enzyme 2 (ACE2) is the host functional receptor for the new
virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different …
virus SARS-CoV-2 causing Coronavirus Disease 2019. ACE2 is expressed in 72 different …
Targeting the renin-angiotensin system to improve cancer treatment: Implications for immunotherapy
Renin-angiotensin system (RAS) inhibitors (RASi)—widely prescribed for the treatment of
cardiovascular diseases—have considerable potential in oncology. The RAS plays a crucial …
cardiovascular diseases—have considerable potential in oncology. The RAS plays a crucial …
Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown diverse life-
threatening effects, most of which are considered short-term. In addition to its short-term …
threatening effects, most of which are considered short-term. In addition to its short-term …
The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …
Ki67 changes identify worse outcomes in residual breast cancer tumors after neoadjuvant chemotherapy
P Cabrera‐Galeana, W Muñoz‐Montaño… - The …, 2018 - academic.oup.com
Background Several breast cancer (BC) trials have adopted pathological complete response
(pCR) as a surrogate marker of long‐term treatment efficacy. In patients with luminal …
(pCR) as a surrogate marker of long‐term treatment efficacy. In patients with luminal …
Do renin–angiotensin system inhibitors influence the recurrence, metastasis, and survival in cancer patients?: Evidence from a meta-analysis including 55 studies
H Sun, T Li, R Zhuang, W Cai, Y Zheng - Medicine, 2017 - journals.lww.com
Background: Renin–angiotensin system inhibitors (RAS inhibitors) are antihypertensive
agents with potential antitumor effects. However, various studies have yielded conflicting …
agents with potential antitumor effects. However, various studies have yielded conflicting …
Oncogenic potential of SARS-CoV-2—targeting hallmarks of cancer pathways
A Jaiswal, S Shrivastav, HR Kushwaha… - Cell Communication and …, 2024 - Springer
The 2019 outbreak of SARS-CoV-2 has caused a major worldwide health crisis with high
rates of morbidity and death. Interestingly, it has also been linked to cancer, which begs the …
rates of morbidity and death. Interestingly, it has also been linked to cancer, which begs the …
The effect of local renin angiotensin system in the common types of cancer
The Renin Angiotensin System (RAS) is a hormonal system that is responsible for blood
pressure hemostasis and electrolyte balance. It is implicated in cancer hallmarks because it …
pressure hemostasis and electrolyte balance. It is implicated in cancer hallmarks because it …
The role of angiotensin II in cancer metastasis: Potential of renin-angiotensin system blockade as a treatment for cancer metastasis
S Ishikane, F Takahashi-Yanaga - Biochemical Pharmacology, 2018 - Elsevier
Hypertension, which often exists as a comorbid condition in cancer patients, is considered
as a factor affecting cancer progression. The renin-angiotensin system (RAS) plays an …
as a factor affecting cancer progression. The renin-angiotensin system (RAS) plays an …
Association between angiotensin-converting enzyme inhibitors and lung cancer—a nationwide, population-based, propensity score-matched cohort study
Background: Direct evidence of lung cancer risk in Asian users of angiotensin-converting
enzyme inhibitors (ACEIs) is lacking. Methods: The ACEI cohort comprised 22,384 patients …
enzyme inhibitors (ACEIs) is lacking. Methods: The ACEI cohort comprised 22,384 patients …