Epithelial-to-mesenchymal transition (EMT) is a key step in development, wound healing,
and cancer development. It involves cooperation of signaling pathways, such as …

Tissue integrity is maintained by the stroma in physiology. In cancer, however, tissue
invasion is driven by the stroma. Myofibroblasts and cancer‐associated fibroblasts are …

Cancer-associated fibroblasts (CAFs) are activated fibroblasts in the tumor
microenvironment. They are one of the most prominent cell types in the stroma and produce …

Several clinical trials have recently targeted specific pathways implicated in the
pathogenesis of idiopathic pulmonary fibrosis (IPF). However, IPF remains plagued by a …

The number of descriptions of emerging viruses has grown at an unprecedented rate since
the beginning of the 21 st century. Severe acute respiratory syndrome coronavirus 2 (SARS …

Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive
fibrosing interstitial pneumonia of unknown cause, occurring primarily in older adults, and …

Idiopathic pulmonary fibrosis (IPF) is characterized by the progressive and ultimately fatal
accumulation of fibroblasts and extracellular matrix in the lung that distorts its architecture …

In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …

Idiopathic pulmonary fibrosis (IPF) is a worldwide disease characterized by the chronic and
irreversible decline of lung function. Currently, there is no drug to successfully treat the …

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an appalling
prognosis. The failure of anti-inflammatory therapies coupled with the observation that …