Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …

Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …

White adipose tissue (WAT) plays an important role in the integration of whole-body
metabolism by storing fat and mobilizing triacylglycerol when needed. The released free …

Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …

Numerous studies have highlighted the key roles of oxidative stress and inflammation in
aging‐related diseases such as obesity, type 2 diabetes, age‐related macular degeneration …

Calcium (Ca 2+) is an essential ligand that binds its primary intracellular receptor calmodulin
(CaM) to trigger a variety of downstream processes and pathways. Central to the actions of …

Caenorhabditis elegans (C. elegans) is a free-living nematode that has been extensively
utilized as an animal model for research involving aging and neurodegenerative diseases …

Endometrial cancer is the most common malignancy of the female genital tract. Obesity is a
strong risk factor for endometrial cancer. Adipose tissue is an active endocrine organ that …

Non-alcoholic fatty liver disease (NAFLD) is an increasingly prevalent ailment worldwide.
Moreover, de novo lipogenesis (DNL) is considered a critical factor in the development of …

Lung cancer (LC) is a leading cause of death worldwide with high mortality and morbidity. A
wide variety of risk factors are considered for LC development such as smoking, air pollution …