[HTML][HTML] The opportunities and challenges of using Drosophila to model human cardiac diseases

Y Zhao, J van de Leemput, Z Han - Frontiers in Physiology, 2023 - frontiersin.org
The Drosophila heart tube seems simple, yet it has notable anatomic complexity and
contains highly specialized structures. In fact, the development of the fly heart tube much …

[HTML][HTML] Multiomics and bioinformatics identify differentially expressed effectors in the brain of Toxoplasma gondii infected masked palm civet

H Yuan, T Jiang, WD Zhang, Z Yang, S Luo… - Frontiers in cellular …, 2023 - frontiersin.org
Introduction The masked palm civet (Paguma larvata) serves as a reservoir in transmitting
pathogens, such as Toxoplasma gondii, to humans. However, the pathogenesis of T. gondii …

[HTML][HTML] Luteolin and triptolide: Potential therapeutic compounds for post-stroke depression via protein STAT

T Zhao, S Sun, Y Gao, Y Rong, H Wang, S Qi, Y Li - Heliyon, 2023 - cell.com
Post stroke depression (PSD) is a common neuropsychiatric complication following stroke
closely associated with the immune system. The development of medications for PSD …

[HTML][HTML] scRNA-seq reveals the diversity of the developing cardiac cell lineage and molecular players in heart rhythm regulation

KA Nahia, A Sulej, M Migdał, N Ochocka, R Ho… - Iscience, 2024 - cell.com
We utilized scRNA-seq to delineate the diversity of cell types in the zebrafish heart.
Transcriptome profiling of over 50,000 cells at 48 and 72 hpf defined at least 18 discrete cell …

[HTML][HTML] Capturing heart valve development with Gene Ontology

SH Ahmed, AT Deng, RP Huntley, NH Campbell… - Frontiers in …, 2023 - frontiersin.org
Introduction: The normal development of all heart valves requires highly coordinated
signaling pathways and downstream mediators. While genomic variants can be responsible …

[HTML][HTML] Endocrine and scavenging cell functions of a juvenile fish heart atrium: Fine structure aspects and translating conjectures

J Gilloteaux, L Jennes, JJ Vanderhaeghen - Translational Research in …, 2023 - Elsevier
Background The atrium of the juvenile teleost, smallmouth bass, Micropterus dolomieu
Lacépède showed a pigmented endocardium. Our goal was to use fine structure to survey …

[HTML][HTML] Advances and Prospects in Understanding Vertebrate Cardiac Conduction System, Pacemaker Cell, and Cardiac Muscle Development: Toward Novel …

RO Bello, S Frew, Y Siddiqui, R Minhas - Muscles, 2023 - mdpi.com
The heart is composed of muscle cells called cardiomyocytes, including a specialized
population named pacemaker cells that form the cardiac conduction system (CCS), which is …

Gene annotation: Resources for the heart

RC Lovering - Genomic and Molecular Cardiovascular Medicine, 2024 - Elsevier
Gene annotations are essential to facilitate analyses and interpretation of high-throughput
biological datasets. Many different gene annotation resources have been developed over …

The development of specialised cardiac muscle cells within a vertebrate heart requires a specialised regulatory network

S Frew, Y Siddiqui, R Minhas - 2023 - preprints.org
Heart is composed of muscle cells called cardiomyocytes, including a specialized
population, named pacemaker cells, that form the Cardiac Conduction System (CCS) …