Background Nearly a quarter of patients with locally advanced (T4 stage) or perforated colon
cancer are at risk of developing peritoneal metastases, often without curative treatment …

Simple Summary Cancer that spreads to the lining of the abdomen, the peritoneum, is
currently treated with heated chemotherapy and surgery. However, the effects of the high …

Background The randomized trial PRODIGE 7 failed to show the benefit of oxaliplatin
hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal peritoneal metastasis …

Developing chemotherapeutic resistance affects clinical outcomes of oxaliplatin treatment
on various types of cancer. Thus, it is imperative to explore alternative therapeutic strategies …

Purpose Hydrogel films have been extensively studied for controlled drug delivery for cancer
treatment. Moreover, hydrogels are widely used for wound-healing effects and to prevent …

Peritoneal metastases confer the worst survival among all sites in patients with metastatic
colorectal cancer. They develop largely through transcoelomic spread, with a sequence of …

Background Cisplatin (CDDP)-containing hyperthermic intraperitoneal chemotherapy
(HIPEC) is frequently applied in selected patients with peritoneal malignancies derived from …

Background Peritoneal metastases (PM) commonly occur in colorectal cancer patients.
Systemic chemotherapy yields poor outcomes for these patients. It is hypothesised that …

Background and objectives Cytoreductive surgery (CRS) with hyperthermic intraperitoneal
chemotherapy (HIPEC) can offer selected patients with colorectal peritoneal metastases …

Cytoreductive surgery (CRS) is effective for colorectal cancer peritoneal metastases (CRPM)
at increasing overall survival (OS) compared to systemic anti-cancer treatment (SACT) …