Amino acids are widely distributed in biological fluids and involved in many biological
processes, such as the synthesis of proteins, fatty acids, and ketone bodies. The altered …

Click chemistry is an approach that uses efficient and reliable reactions to bind two
molecular building blocks and avoids the formation of byproducts. It has become …

Determination of the amino acid phenylalanine is important for lifelong disease
management in patients with phenylketonuria, a genetic disorder in which phenylalanine …

An off-the-shelf Agilent 7100 capillary electrophoresis (CE) instrument was employed for the
automated processing and analysis of dried blood spots (DBSs) collected by Capitainer® B …

Phenylketonuria (PKU) is a genetically inherited disease caused by a mutation of the gene
encoding phenylalanine hydroxylase (PAH) and is the most common inborn error of amino …

Background The modern management of phenylketonuria (PKU) consists of generalized
newborn screening (NBS) for hyperphenylalaninemia (HPA), confirmation of HPA in children …

In present study, novel graphene oxide (GO)-ɛ-MnO 2 microspheres with homogeneous
flaky texture were synthesized by a precursor conversion method and bound to activated …

Inborn errors of metabolism (IEM) are a group of about 500 rare genetic diseases with large
diversity and complexity due to number of metabolic pathways involved in. Establishing a …

This study aimed to develop a fast, accurate, and precise high‐performance liquid
chromatography with UV detection method for simultaneous analysis of underivatized …

Argininosuccinic aciduria is an autosomal, recessive amino acid disorder that is caused by a
deficiency of the argininosuccinate lyase enzyme. Citrulline is the most significant marker to …