Oxidative stress and inflammation are two critical pathological processes of cerebral
ischemia-reperfusion injury. Myeloperoxidase (MPO) is a critical inflammatory enzyme and …

Cerebral ischemia-reperfusion injury can lead to a series of serious brain diseases and
cause death or different degrees of disability. Polysaccharide is a kind of biological …

Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …

Brain ischemia and reperfusion (I/R) is one of the most severe clinical manifestations of
ischemic stroke, placing a significant burden on both individuals and society. The only FDA …

Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are
involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease …

Plant exosome-like nanoparticles (ELNs) have shown great potential in treating tumor and
inflammatory diseases, but the neuroprotective effect of plant ELNs remains unknown. In the …

It is estimated that in 2017 there were 451 million people with diabetes worldwide. These
figures are expected to increase to 693 million by 2045; thus, innovative preventative …

Background The leakage of blood-brain barrier (BBB) is main pathophysiological change in
acute stage of ischemic stroke, which not only deteriorates neurological function, but also …

MicroRNAs (miRNAs) have been widely reported to induce posttranscriptional gene
silencing and led to an explosion of new strategies for the treatment of human disease. It has …