Molecular and non‐invasive imaging are rapidly emerging fields in preclinical cancer drug
discovery. This is driven by the need to develop more efficacious and safer treatments, the …

Contrast-enhanced ultrasound (CEUS) with microbubble contrast agents is a new imaging
technique for quantifying tissue perfusion. CEUS presents several advantages over other …

Initially, a set of guidelines for the use of ultrasound contrast agents was published in 2004
dealing only with liver applications. A second edition of the guidelines in 2008 reflected …

Purpose To develop and implement an evidence-based protocol for characterizing vascular
response of renal cell carcinoma (RCC) to targeted therapy by using dynamic contrast …

Dynamic contrast‐enhanced ultrasound (US) imaging, a technique that uses microbubble
contrast agents with diagnostic US, has recently been technically summarized and reviewed …

Objectives Actively targeting ultrasound contrast agents to tumor vasculature improves
contrast‐enhanced sonography of tumor angiogenesis. This report summarizes an …

Purpose Pluronic has been shown to sensitize various tumor cell lines to chemotherapy and
hyperthermia by altering the membrane fluidity, depleting ATP, and modulating the heat …

Objectives The purposes of this study were to assess the reliability of parametric maps from
dynamic contrast-enhanced ultrasound (DCE-US) to reflect the heterogeneous distribution …

Ultrasound contrast imaging techniques represent a real opportunity to improve efficiency in
the preclinical drug discovery and development process. Ultrasound contrast agents (UCAs) …

Ultrasound is one of the workhorses in clinical cancer diagnosis. In particular, it is routinely
used to characterize lesions in liver, urogenital tract, head and neck and soft tissues. During …